Results 51 to 60 of about 124,617 (305)

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Oxytocin in the Male Reproductive Tract; The Therapeutic Potential of Oxytocin-Agonists and-Antagonists

Frontiers in Endocrinology, 2020
In this review, the role of oxytocin and oxytocin-like agents (acting via the oxytocin receptor and belonging to the oxytocin-family) in the male reproductive tract is considered.
Beatrix Stadler, Michael R. Whittaker, Betty Exintaris, Ralf Middendorff   +3 more
doaj   +1 more source

Epidural Analgesia With or Without Oxytocin, but Not Oxytocin Alone, Administered During Birth Disturbs Infant Pre-feeding and Sucking Behaviors and Maternal Oxytocin Levels in Connection With a Breastfeed Two Days Later

Frontiers in Neuroscience, 2021
Aims This work aimed to study consequences of medical interventions in connection with birth on infant pre-feeding and feeding behaviors and on maternal oxytocin levels in connection with a breastfeed 2 days later.Materials and Methods Mothers and their ...
Yuki Takahashi, Kerstin Uvnäs-Moberg, Eva Nissen, Lena Lidfors, Anna-Berit Ransjö-Arvidson, Wibke Jonas   +5 more
doaj   +1 more source

Regulators of G protein signalling proteins in the human myometrium [PDF]

, 2009
The contractile state of the human myometrium is controlled by extracellular signals that promote relaxation or contraction. Many of these signals function through G proteincoupled receptors at the cell surface, stimulating heterotrimeric G proteins and ...
Abramow-Newerly, Ballon, Bansal, Benians, Bernstein, Blanks, Brodt-Eppley, Chatterjee, Cho, De Vries, Dohlman, Druey, Europe-Finner, Georgoussi, Graham Ladds, Hague, Hao, Hepler, Hill, Hollinger, Hu, John Davey, Koelle, Ladds, Langer, Li, Lopez-Bernal, Manu Vatish, Milligan, Mittmann, Moore, Neitzel, O'Brien, Park, Phaneuf, Plested, Ross, Saitoh, Sanborn, Sevasti Zervou, Snabaitis, Snow, Steven Thornton, Suarez, Tamirisa, Tang, Tinker, Tribe, Wang, Willars, Xie, Xu, Zeng   +52 more
core   +1 more source

Radioimmunoassay for Oxytocin

Endocrinologia Japonica, 1974
A specific and sensitive radioimmunoassay method for oxytocin and its application to the measurement of human plasma oxytocin levels are described. Antiserum tooxytocin was prepared in guinea pigs by repeated subcutaneous injections of synthetic oxytocin emulsified in complete Freund's adjuvant.
H, Kato, T, Torigoe
openaire   +3 more sources

An overview of the oxytocin-oxytocin receptor signaling network [PDF]

Journal of Cell Communication and Signaling, 2016
Oxytocin, a nine amino acid long neuropeptide hormone, is synthesized in the hypothalamus and stored and released from the neural lobe of the pituitary gland. Although commonly known for its central role in the regulation of parturition and lactation, oxytocin signaling also plays a key role in modulating social behavior, evoking contentment ...
Oishi, Chatterjee, Krutika, Patil, Apeksha, Sahu, Lathika, Gopalakrishnan, Praseeda, Mol, Jayshree, Advani, Srabani, Mukherjee, Rita, Christopher, T S Keshava, Prasad   +8 more
openaire   +2 more sources

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

Angewandte Chemie, EarlyView.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Emergent synchronous bursting of oxytocin neuronal network. [PDF]

PLoS Computational Biology, 2008
When young suckle, they are rewarded intermittently with a let-down of milk that results from reflex secretion of the hormone oxytocin; without oxytocin, newly born young will die unless they are fostered.
Enrico Rossoni, Jianfeng Feng, Brunello Tirozzi, David Brown, Gareth Leng, Françoise Moos   +5 more
doaj   +1 more source

Oxytocin attenuates microglial activation and restores social and non-social memory in APP/PS1 Alzheimer model mice

iScience, 2023
Summary: Alzheimer’s disease (AD) is characterized by neurodegeneration, memory loss, and social withdrawal. Brain inflammation has emerged as a key pathogenic mechanism in AD.
Maria Clara Selles, Juliana T.S. Fortuna, Yasmin P.R. de Faria, Luciana Domett Siqueira, Ricardo Lima-Filho, Beatriz M. Longo, Robert C. Froemke, Moses V. Chao, Sergio T. Ferreira   +8 more
doaj   +1 more source