Results 271 to 280 of about 24,748 (316)

Oxytocin, oxytocin-associated neurophysin and the oxytocin receptor in the human prostate

Cell and Tissue Research, 2004
Oxytocin has been implicated in the regulation of prostate growth. However, the cellular localisation of oxytocin in the normal and diseased human prostate is not known. Oxytocin, oxytocin-associated neurophysin and oxytocin receptor were detected by immunohistochemistry in tissues from patients undergoing routine prostatectomy and in normal human ...
Whittington, K, Assinder, S, Gould, M, Nicholson, H   +3 more
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Loss of myometrial oxytocin receptors during oxytocin-induced and oxytocin-augmented labour

Reproduction, 2000
Oxytocin is used widely for the induction and augmentation of labour, but there is little information about the dynamics of oxytocin receptors in human myometrium during parturition, and the possible effect of oxytocin infusion. This information is important because G protein-coupled receptors, such as the oxytocin receptor, undergo desensitization ...
S, Phaneuf, B, Rodríguez Liñares, R L, TambyRaja, I Z, MacKenzie, A, López Bernal   +4 more
openaire   +2 more sources

Oxytocin and Oxytocin Receptor Gene Expression in the Uterus

1995
Publisher Summary The posterior pituitary contains a strong uterotonic activity known as the nonapeptide oxytocin (OT). It has been determined that uterus itself represents a major site of OT production. Therefore, the activation of uterine contractions by circulating OT is only one aspect of OT action. A significant portion of OT activity originates
H H, Zingg, F, Rozen, K, Chu, A, Larcher, A, Arslan, S, Richard, D, Lefèbvre   +6 more
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Oxytocin receptors in rat oviduct

Biochemical and Biophysical Research Communications, 1975
The binding of tritiated oxytocin was studied in rat oviduct homogen ates sedimenting between 1000 X g for 10 minutes and 48000 X g for 30 minutes. Results showed that oxytocin is specifically bound to oviducal particles with high affinity. In particles prepared from estrogen-treated rats apparent Kd for oxytocin binding was 1.8 X 10 M.
openaire   +2 more sources

Oxytocin Antagonist (dTVT) and Oxytocin Receptors in Myometrium and Decidua

American Journal of Perinatology, 1989
To investigate whether a putative oxytocin (OT) receptor blocker 1-deamino-[2-D-tyrosine (OEt)-4 threonine-8-ornithine]oxytocin (dTVT) inhibits OT binding to its receptors, we studied binding of [3H]OT to late-pregnant human, guinea pig, and rat myometrial and decidual membranes and competition of dTVT with this binding.
A R, Fuchs, A, Vangsted, M, Ivanisevic, K, Demarest   +3 more
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Molecular evolution of the oxytocin–oxytocin receptor system in eutherians

Molecular Phylogenetics and Evolution, 2013
Oxytocin (OXT) is a nine-amino-acid peptide hormone that is mainly released at the times of uterine contractions during parturition and milk ejection during lactation, whereas a similar peptide hormone, arginine vasopressin, primarily exerts direct antidiuretic action on the kidney and causes vasoconstriction of the peripheral vessels. The genes coding
Kaoru, Yamashita, Takashi, Kitano
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Endogenous oxytocin inhibits morphine tolerance through limbic forebrain oxytocin receptors

Brain Research, 1988
It has previously been shown that endogenous oxytocin (OXT) inhibits the development of acute morphine tolerance. The role of OXT receptors in the central nervous system (CNS) was therefore studied by using a specific OXT receptor antagonist, N-acetyl-(2-O-methyltyrosin)-OXT (ACME-OXT). ACME-OXT (1 pg) was injected into the posterior olfactory nucleus,
Z, Sarnyai, S, Viski, M, Kriván, G, Szabó, G L, Kovács, G, Telegdy   +5 more
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Functional Architecture of Vasopressin/Oxytocin Receptors

Journal of Receptors and Signal Transduction, 1999
Three-dimensional models of G protein-coupled receptors (GPCR) have been defined using most experimental data available and protein modeling techniques. The endogenous ligand binding sites have been qualitatively described and putative receptor activation mechanisms have been proposed.
M, Hibert, J, Hoflack, S, Trumpp-Kallmeyer, B, Mouillac, B, Chini, E, Mahé, N, Cotte, S, Jard, M, Manning, C, Barberis   +9 more
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Oxytocin Receptors and Neurobehavior

2016
Research across species has shown that the neuropeptide oxytocin plays a key role in the regulation of social cognition and behavior. It is important for attachment, social exploration, and social recognition, as well as anxiety and stress-related behaviors. Based on oxytocin administration studies and measurements of peripheral oxytocin levels, it has
Robert Kumsta, Johannes C. S. Zang, Dirk Moser   +2 more
openaire   +1 more source

Oxytocin Receptors in Bovine Mammary Tissue

Journal of Receptor Research, 1987
Oxytocin receptors were identified and characterized in bovine mammary tissue. [3H]-oxytocin was specifically bound to the 105,000 X g particulate fractions from 5 lactating cows and 5 non-lactating cows. Binding reached equilibrium by 50 min at 20 degrees C and by 8 hr at 4 degrees C.
X, Zhao, R C, Gorewit
openaire   +2 more sources