Results 151 to 160 of about 30,661 (234)
CHD4 epigenetically coordinates genomic instability and immunosuppression to drive pan-cancer progression and confer HDAC inhibitor sensitivity. [PDF]
Clin Exp MedFu G +7 more
europepmc +1 more source
British Journal of Haematology, EarlyView.This nationwide study of 56 patients with Down syndrome‐associated acute lymphoblastic leukaemia (ALL) demonstrated that haematopoietic stem cell transplantation (HSCT) in complete remission (CR)1/2 yields comparable event‐free survival to non‐Down syndrome ALL.
Hisashi Ishida +24 more
wiley +1 more source
Mn Oxide Nanowire/ZIF-8 Composites with Multiple Enzyme-like Activities for Enantioselective Glutamate Sensing. [PDF]
Biosensors (Basel)Chen GY, Luo ML, Dai JJ, Yang FQ.
europepmc +1 more source
Brain Pathology, EarlyView.Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince +12 more
wiley +1 more source
Cancer Science, EarlyView.Copy number variation analysis in The Cancer Genome Atlas identified NTAQ1 as a potential driver of HCC progression. NTAQ1 accelerates tumor growth by promoting the degradation of the tumor suppressor protein PRDM2, thereby impairing DNA repair and suppressing apoptosis. These findings indicate that NTAQ1 could be a valuable target for the treatment of
Tomohiko Ikehara +21 more
wiley +1 more source
RUNX1‐Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells
Cancer Science, EarlyView.RUNX1 transcriptionally activates CPXM1, promotes EMT, and enhances the proliferation, invasion, and metastasis of gastric cancer cells. ABSTRACT Gastric cancer (GC) remains a leading cause of cancer‐related mortality worldwide, with current treatment strategies largely limited to surgery, chemotherapy, and targeted therapy.
Ping Jia +8 more
wiley +1 more source
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu +15 more
wiley +1 more source
Clinical Oral Implants Research, EarlyView.ABSTRACT To assess the 5‐year dimensional stability of buccal hard‐tissues following guided bone regeneration (GBR) of peri‐implant dehiscence defects using deproteinized bovine bone mineral (DBBM) blocks or particulate. Methods Patients requiring single‐tooth implants and presenting a buccal dehiscence defect (≥ 3 mm) at implant placement were ...
Anina N. Zuercher +5 more
wiley +1 more source
Conservation Science and Practice, EarlyView.Biodiversity offsetting should be based on adequately large multipliers to deliver no net loss or a net gain for biodiversity, yet the multipliers are often applied without quantitative assessment of the ecological outcomes of offset actions. Here, we show how ecologically realistic offset multipliers were defined based on ecological response estimates
Joel Jalkanen +7 more
wiley +1 more source