Results 131 to 140 of about 13,905 (231)

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

open access: yesAllergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama   +16 more
wiley   +1 more source

Ficolo Oy

open access: yes, 2019
Category: Second Opinion, Sector: Information and Communication Technology (ICT), Issuer type: Corporate, Shading: Dark ...
openaire   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

open access: yesAllergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert   +9 more
wiley   +1 more source

Dietary Habits and Atopic Dermatitis Significantly Influence the Fecal Microbiome

open access: yesAllergy, EarlyView.
Atopic dermatitis, dietary habits, sex, and BMI significantly influenced the fecal microbiome composition. On the species level, Faecalibacterium taiwanense was more abundant in atopic dermatitis, and Vescimonas sp000435555 was more abundant in the control population. On the genus level, CAG‐302 (NCBI: Clostridium) was more abundant in controls.
Danielle Fehr   +14 more
wiley   +1 more source

Oncovascular Resection in Pelvic Exenteration: A Systematic Review

open access: yesANZ Journal of Surgery, EarlyView.
Risk of bias assessment using ROBINS‐1 V2. Selection of the reported result (D7) was judged based on omission of key expected outcomes, including margin status (R0 resection), postoperative complications and mortality. Studies not reporting these outcomes were classified as serious risk of bias, while those with broadly complete but non‐pre‐specified ...
Joshua Richard Burke   +6 more
wiley   +1 more source

Real‐world insights on switching aflibercept dosage for enhanced outcomes in age‐related macular degeneration (RISE‐AMD): Safety data

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan   +12 more
wiley   +1 more source

Childhood ocular safety after postnatal exposure to topical dexamethasone during retinopathy of prematurity screening

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Dexamethasone eye drops are being introduced off‐label to prevent progression of severe retinopathy of prematurity (ROP). We evaluated ophthalmologic outcomes in early childhood after postnatal topical dexamethasone exposure in pre‐term infants at a standardized follow‐up examination.
Mariya Petrishka‐Lozenska   +3 more
wiley   +1 more source

Regional growth kinetics of geographic atrophy in age‐related macular degeneration with and without fovea‐sparing

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Fovea‐sparing geographic atrophy (GA) patients retain near‐normal central vision. To better understand GA progression in relation to the fovea, we performed a semi‐automated image analysis of regional atrophy growth in a long‐term GA natural‐history cohort. Methods Prospective‐observational, single‐centre‐study (02/2013–07/2025) at the
Daniel R. Muth   +8 more
wiley   +1 more source

In Vitro Performance of Valved Holding Chambers in Paediatric Asthma Controller Therapy

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Research on the drug delivery of inhaled corticosteroids and combination medications via valved holding chambers (VHCs) with children's breathing patterns is limited. We aimed to evaluate the in vitro performance of commercially available VHCs without facemasks under preschooler breathing conditions, focusing on total delivered dose and ...
Laura Ojanperä   +2 more
wiley   +1 more source

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