Results 191 to 200 of about 70,925 (234)

Angiogenic and Stromal Remodeling Associated With Aggressive Fibrosarcomatous Dermatofibrosarcoma Protuberans

open access: yesCancer Science, EarlyView.
FS‐DFSP exhibits coordinated angiogenic and stromal remodeling characterized by immature vascular features, CAF accumulation, and enhanced macrophage infiltration. VEGFA, CCL2, and CXCR4 may contribute to this tumor‐promoting microenvironment. ABSTRACT Although collagen type 1 alpha 1 (COL1A1)–platelet‐derived growth factor B‐chain (PDGFB) gene fusion ...
Sakura Shiraishi   +11 more
wiley   +1 more source

Japanese Society for Hereditary Tumors Guidance: Hereditary Cancer Syndromes With Multigene Panel Testing, 2025 Edition

open access: yesCancer Science, EarlyView.
Schematic of the clinical algorithm for diagnosing hereditary cancer syndromes using MGPT. ABSTRACT In March 2025, the Japanese Society for Hereditary Tumors and the Ministry of Health, Labour and Welfare (MHLW) Research on Promotion of Cancer Control Program Grant Number JPMH 23EA1037 published the “Japanese Society for Hereditary Tumors Guidance ...
Reiko Yoshida   +66 more
wiley   +1 more source

3‐Indoxyl Sulfate and O‐Acetylcarnitine Are Potential Novel Biomarkers for Early Diagnosis of Esophageal Cancer

open access: yesCancer Science, EarlyView.
Through comprehensive analysis of plasma and urine from patients with esophageal cancer and healthy controls, 3‐indoxyl sulfate and O‐acetylcarnitine were identified as metabolites significantly associated with esophageal cancer. These metabolites were elevated in patients and demonstrated promising diagnostic performance for early detection.
Kenji Hamada   +8 more
wiley   +1 more source

Women's academic leadership and the governance of digital public health systems: an opinion

open access: yesFrontiers in Public Health
Muthu Kumari   +3 more
doaj   +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

open access: yesClinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto   +121 more
wiley   +1 more source

Subcutaneous Allergen Immunotherapy With Thermosensitive Hydrogel and Recombinant Birch Pollen Allergen Variant, a Randomised Controlled Trial

open access: yesClinical &Experimental Allergy, EarlyView.
A Phase 1, randomised, placebo‐controlled, dose‐escalation trial was performed with 30 birch pollen allergic subjects treated with DM‐101PX, that contains a recombinant hypoallergenic variant of Bet v 1 formulated with poloxamer 338 thermosensitive hydrogel.
Anna Nilson   +14 more
wiley   +1 more source

Immersive virtual reality arm exercise, physical activity, and cardiometabolic health in cerebral palsy: A phase 1 trial

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
In this pilot randomized trial, 32 young people with cerebral palsy used seated, telehealth‐delivered virtual reality exergaming for 12 weeks. Participants averaged 144 minutes per week of exercise and self‐reported physical activity increased by up to 166%, with favorable early changes in insulin (−45%) and triglycerides (−20%), while a waitlist ...
Byron Lai   +10 more
wiley   +1 more source

Nutrient‐specific combinatorial secretion of GLP‐1 and neurotransmitters in the enteroendocrine L‐cell line GLUTag

open access: yesThe FEBS Journal, EarlyView.
Enteroendocrine L cells function as chemosensors in the intestine. Using the L‐cell line GLUTag, we show that distinct nutrients trigger different combinations of co‐secretion of GLP‐1 and neurotransmitters: D‐glucose evokes GLP‐1, glutamate, and ATP; L‐glutamine evokes GLP‐1 and glutamate; sucralose and butyrate evoke only GLP‐1.
Yo Ito   +5 more
wiley   +1 more source

Does Survey Angling CPUE Reflect Population Density of Northern Pike (Esox lucius) in Small Boreal Lakes?

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Knowing the relationship between catch per unit effort (CPUE) and population density is crucial for the management of recreational fisheries. We conducted standardized angling for pike in 16 lakes (3.4–22.1 ha) to test whether lure type, color, and pike density affect CPUE and the size of captured fish.
Aatu Turunen   +3 more
wiley   +1 more source

Do Habitat Restoration Efforts and the Associated Releases of Hatchery‐Reared Fish Affect the Genetic Diversity and Integrity of Native Brown Trout Populations?

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Habitat restoration may protect brown trout (Salmo trutta) populations from loss of genetic diversity by increasing environmental carrying capacity and, consequently, population size. However, the accompanying release of hatchery‐reared fish may threaten the genetic integrity of native populations through introgression.
Noor Alwash   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy