Results 141 to 150 of about 69,566 (235)

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani   +5 more
wiley   +1 more source

Asiakaskokemuksen kehittäminen: Mercatus Oy [PDF]

open access: yes, 2019
Tämän opinnäytetyön tavoitteena on pohtia asiakaskokemusta: mistä se muodostuu ja millaiset asiat siihen vaikuttavat. Työ koostuu teoriaosuudesta sekä asiakastyytyväisyystutkimuksesta, mikä on tehty toimeksiantajayritykselle Mercatus Oy:lle.
Juntunen, Mikko-Matias
core  

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Roll‐to‐Roll Processing of Biodegradable Multilayer Barrier Packaging Structures

open access: yesPackaging Technology and Science, EarlyView.
This work demonstrates that novel packaging materials built using biobased and biodegradable materials can be produced in pilot‐scale and converted into functional barrier packaging. The proposed structures are anticipated to make a strong impact in use‐cases where the risk of environmental littering is elevated, such as snacks and take away meals ...
Enni Luoma   +5 more
wiley   +1 more source

Työturvallisuussuunnitelma : Are Oy

open access: yes
Tässä työssä käsitellään rakennustyömaan työturvallisuussuunnittelua päätoteuttajan näkökulmasta. Työn tavoitteena oli selvittää rakennustyömaan päätoteuttajaa koskevat velvollisuudet työturvallisuussuunnittelun osalta, sekä toiminnallisena osuutena ...
Lintunen, Senni
core  

The Impact of ESG on Green Innovation: The Mediating Roles of Digitalization and Information Disclosure

open access: yesSustainable Development, EarlyView.
ABSTRACT This study examines how ESG performance influences green innovation, focusing on its underlying mechanisms and heterogeneous effects across firms and regions. Using panel data for Chinese A‐share listed companies from 2009 to 2023, we employ a two‐way fixed effects model and use ESG fund exposure as an instrumental variable to support causal ...
Yingying Ouyang   +4 more
wiley   +1 more source

Oy Sözleşmeleri [PDF]

open access: yes
Nowadays, it is common for companies with economic and social importance to want to be managed by partners. The only way for partners to have a say in the management of the company of which they are stakeholders, and for general assembly decisions to be taken in line with their wishes on critical issues, is to have sufficient voting rights.
openaire  

Investigation of Serrated Flow in Intercritically Annealed Medium Manganese Steel by In Situ Synchrotron X‐Ray Diffraction

open access: yessteel research international, EarlyView.
Serrations and stepwise austenite phase transformation were observed in cold‐rolled and annealed medium manganese steels. By in situ XRD experiments, these two phenomena were studied simultaneously. The results show that DSA leads to the creation of PLC bands and load drops in the specimen.
Shahroz Ahmed   +6 more
wiley   +1 more source

Taloyhtiöiden putkiremonttihankkeiden vastuullisuuden edistäminen: Eerika Consulting Oy [PDF]

open access: yes
Tämän opinnäytetyön tavoitteena oli edistää taloyhtiöiden putkiremonttihankkeiden vastuullisuutta kehittämällä rakennusalan konsulttiyritys Eerika Consulting Oy:n toimintatapoja niissä.
Lakimo, Nina
core  

Strain‐Induced NbC Precipitation as a Governing Mechanism for Hot Deformation Resistance in CrNiMnMoB Ultrahigh‐Strength Steels

open access: yessteel research international, EarlyView.
Strain‐induced NbC precipitation governs hot‐deformation resistance in CrNiMnMoB ultrahigh‐strength steel by suppressing dynamic recrystallization, increasing activation energy, and refining martensitic substructures. The precipitation response is controlled by temperature, supersaturation, and strain rate, with slow deformation promoting extensive NbC
Atef Hamada   +6 more
wiley   +1 more source

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