Cancer Science, EarlyView.Copy number variation analysis in The Cancer Genome Atlas identified NTAQ1 as a potential driver of HCC progression. NTAQ1 accelerates tumor growth by promoting the degradation of the tumor suppressor protein PRDM2, thereby impairing DNA repair and suppressing apoptosis. These findings indicate that NTAQ1 could be a valuable target for the treatment of
Tomohiko Ikehara +21 more
wiley +1 more source
Transition Metal-Based Oxidation Catalysts to Mitigate Methane Emissions from Low-Concentration Sources. [PDF]
ACS OmegaBazybek N +4 more
europepmc +1 more source
Women's academic leadership and the governance of digital public health systems: an opinion
Frontiers in Public HealthMuthu Kumari +3 more
doaj +1 more source
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Hierarchically Porous Multiphase Si-Based Ceramics with Synergistic Electromagnetic Wave Absorption Mechanisms. [PDF]
Adv Sci (Weinh)Jiang J +5 more
europepmc +1 more source
Clinical Oral Implants Research, EarlyView.ABSTRACT To assess the 5‐year dimensional stability of buccal hard‐tissues following guided bone regeneration (GBR) of peri‐implant dehiscence defects using deproteinized bovine bone mineral (DBBM) blocks or particulate. Methods Patients requiring single‐tooth implants and presenting a buccal dehiscence defect (≥ 3 mm) at implant placement were ...
Anina N. Zuercher +5 more
wiley +1 more source
ChemEmbed: a deep learning framework for metabolite identification using enhanced MS/MS data and multidimensional molecular embeddings. [PDF]
Brief BioinformFaizan-Khan M +17 more
europepmc +1 more source
Enriched Metabolic Phenotyping Refines Phenotypic Resolution of Type 2 Diabetes
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Data‐driven clustering studies of type 2 diabetes (T2D) based on limited routine clinical variables have reproducibly described major metabolic subgroups, including severe insulin‐deficient diabetes (SIDD), severe insulin‐resistant diabetes (SIRD), mild obesity‐related diabetes and mild age‐related diabetes.
Min Wang +6 more
wiley +1 more source
Unveiling the BMI Risk Threshold for Osteoarthritis: Multi‐Database Causal and Nonlinear Evidence
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Objective To characterize the nonlinear relationship between BMI and osteoarthritis (OA), and to identify BMI thresholds that inform precise prevention strategies. Methods This multi‐database study integrated Global burden of disease 2021, National Health and Nutrition Examination Survey 2007–2018, and Genome‐Wide Association Studies.
Shaohong Yu +9 more
wiley +1 more source
Characteristics, treatment patterns, and outcomes of patients with metastatic prostate cancer during 2014-2022 in Pirkanmaa, Finland-an observational study. [PDF]
Ther Adv UrolMoisander M +6 more
europepmc +1 more source