Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Mercosul educacional: an?lise da gest?o educacional na promo??o da integra??o regional [PDF]
This thesis analyzes in the impact of Educational MERCOSUR in the development of educational management in the promotion of regional integration with educational policies, and it had CAPES funding.
Menegatti, Edna
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Controllable synthesize of ZnS/PbS nanostructure and their structural and morphological properties
ZnS is an appealing material with wide potential applications in optoelectronics, sensors, and photocatalysis due to its fascinating properties, low cost, and eco-friendly. In this paper, we report the synthesis of ZnS nanowires and nanorods via a simple
Bassem Assfour +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Testing Actinidia chinensis (kiwi) for susceptibility to plant virus infections.
The susceptibility of Actinidia chinensis Planch. ( K i w i ) t o some of the most comrnon viruses in Italy has been studied under glass-house conditions by mechanical inoculation and aphid transmission.
CACIAGLI P, LOVISOLO, O
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
An?lise de requisitos para o desenvolvimento de um software para avalia??o e gest?o escolar [PDF]
Assuming that school education is a public and subjective right and seeking to question the social function of contemporary public school, this research focuses on the development of an analysis of the requirements needed to assess the social quality ...
Vasques, Rosane F?tima +1 more
core
Phosphino-arene ruthenium complexes containing the phosphorus acid anion {P(=O)(OR)(2)} as P-donor
The cationic complex [Ru(OTf)(P(OH)Ph-2){Ph2P-(eta (6)-arene)}]OTf,2(2a=6'-diphenylphosphino-1'-naphthyl-eta (6)((1-6))-naphthalene, 2b = 6,6'-dimethoxy-2'-diphenylphosphino-eta (6)((1-6))-biphenyl), is shown to react with water/tert-butyl alcohol/THF ...
A. Albinati +3 more
core +1 more source

