Results 61 to 70 of about 38,862,466 (240)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Planos de gest?o escolar em Santa Catarina: a gest?o democr?tica em quest?o [PDF]

, 2019
This research integrates the Educational Policies line of the Specialization Program (PPGE) of the Universidade Federal da Fronteira Sul University (UFFS), campus located in Chapec?
Palú, Janete, Pal?, Janete
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The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

SP09 | LYMPH NODES INVOLVEMENT BY ACUTE MYELOID LEUKEMIA IN MYELODISPLASTIC SYNDROME/MYELOPROLIFERATIVE NEOPLASMS: MORPHOLOGIC DISCORDANCE WITH BONE MARROW DISEASE, CLINICAL AND BIOLOGICAL FEATURES AND THERAPY IMPLICATIONS. A SINGLE CENTRE EXPERIENCE

Haematologica
Extramedullary involvement (EMI) refers to myeloid leukemic cells found outside the blood or bone marrow, more frequently in skin, bone, and lymph nodes; in the literature occurring in 2–9% of AML. EMI have to be confirmed by histopathology, morphology,
V. Carluccio, T.M. Santeramo, G. De Santis, C. Buquicchio, R.M. Miccolis, M. Leo, C.R. Germano, N/A S.Mallano, E. Arcuti, V. Strafella, D. Loconte, G. Tarantini.   +11 more
doaj  

Strictly-posterior thoracotomy: a minimal-access approach for construction of the modified Blalock-Taussig shunt in West African children

The Pan African Medical Journal, 2014
INTRODUCTION: In resource-poor settings, the modified Blalock-Taussig shunt (MBTS) is often performed for symptomatic relief of Fallot's tetralogy. From September 2011, we adopted the strictly posterior thoracotomy (SPOT), a minimal-access technique for ...
Frank Edwin, Baffoe Gyan, Innocent Adzamli, Mark Tettey, Kow Entsua-Mensah, Martin Tamatey, Lawrence Sereboe, Ernest Aniteye, Nana Akyaa-Yao   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Regula????o e desempenho de servi??os p??blicos em regime de concess??o: an??lise do transporte ferrovi??rio de cargas no Brasil p??s-privatiza????es

, 2013
O desenvolvimento do transporte ferrovi??rio no Brasil teve diferentes fases, que foram marcadas por distintas formas de participa????o do Estado na provis??o e regula????o desse servi??o p??blico (incluindo o per??odo em que o mesmo acumulou as duas ...
Souza J??nior, Marcos Sim??o de
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