Results 101 to 110 of about 18,467,463 (203)

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 2003-2018, June 2026.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt   +5 more
wiley   +1 more source

p,p′‑DDE Induces Apoptosis through the Modulation of Tumor Necrosis Factor α in PC12 Cells

open access: yes, 2016
p,p′-DDE, the main metabolite of DDT, is notorious for its persistent and bioaccumulation. It has detrimental effects on the nervous system, while the mechanism is unclear.
Yi Qian (466487)   +3 more
core   +1 more source

Gene expression analysis of largemouth bass exposed to estradiol, nonylphenol, and p,p′-DDE

open access: yesComparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2002
The purpose of this study was to determine the specific expression profile of 132 genes, some of which are estrogen responsive, in largemouth bass (LMB) following exposure to estradiol (E(2)), or to two hormonally active agents, 4-nonylphenol (4-NP) and 1,1-dichloro-2, 2-bis (p-chlorophenyl) ethylene (p,p'-DDE), using gene array technology. The results
Department of Biochemistry and Molecular Biology and Center for Biotechnology, P.O. Box 100156 HC Archer Road, MSB Building, Room MG-42, Gainesville, FL 32610, USA ( host institution )   +4 more
openaire   +3 more sources

A Machine‐Learning Classification for Torlesse Composite Terrane Petrofacies and its Application to Sediment Provenance

open access: yesNew Zealand Journal of Geology and Geophysics, Volume 69, Issue 2, June 2026.
The Torlesse Composite Terrane (TCT) forms many of the mountain ranges in Aotearoa New Zealand and has provided enormous quantities of coarse‐grained sediment to Te Riu‐a‐Maui/Zealandia's basins since the mid‐Cretaceous. Tracing the provenance of these sediments to certain regions of the TCT can indirectly reconstruct exhumation patterns associated ...
Matthew O. Parker   +5 more
wiley   +1 more source

Modeling the Intermediate Flow Regime in Flow‐Compensated Intravoxel Incoherent Motion MRI

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 6, Page 3476-3487, June 2026.
ABSTRACT Purpose The intravoxel incoherent motion (IVIM) model is commonly used to separate the effects of motion related to diffusion and blood microcirculation (perfusion) on the MR signal. Depending on the encoding time (T), it is possible to probe the different temporal regimes of blood motion, which resemble a ballistic flow at short T and a ...
Louise Rosenqvist   +5 more
wiley   +1 more source

Elucidating the Functional and Taxonomic Diversity of Soil Microbial Communities From Three Commercial Soybean Farms in South Africa

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Prior to inoculation of soybeans, South African soils contain no Bradyhizobia that nodulate and fix nitrogen in soybeans. Soybean cultivation with prolonged inoculation resulted in the establishment and dominance of Bradyrhizobia in three soybean farms in South Africa as revealed by a microbial community study using shotgun metagenomics. ABSTRACT Prior
Khumbudzo Ndhlovu   +5 more
wiley   +1 more source

Aqueous uptake and sublethal toxicity of p,p′-DDE in non-feeding larval stages of Antarctic krill (Euphausia superba)

open access: yes, 2012
This study evaluated the toxicological sensitivity of non-feeding larval stages of a key Antarctic species (Antarctic krill, Euphausia superba) to p,p′-dichlorodiphenyl dichloroethylene (p,p′-DDE) exposure.
V.K. Kukkonen, Jussi   +17 more
core   +1 more source

RMSE values for BRT models of HCB, β-HCH, Trans-nonachlor, p,p’-DDE and p,p’-DDT.

open access: yes, 2019
RMSE values for BRT models of HCB, β-HCH, Trans-nonachlor, p,p’-DDE and p,p’-DDT.
Kerrie Mengersen (177006)   +3 more
core   +1 more source

CYTOTOXICITY AND DECREASED CORTICOSTERONE PRODUCTION IN ADRENOCORTICAL CELLS BY METHYLSULPHONATED DERIVATIVES OF p,p′-DDE

open access: yes, 2007
3-methylsulphonyl-DDE (3-MeSO2-DDE) undergoes bioactivation by cytochrome P450 11B1 (CYP11B1) in the adrenal cortex of several animal species in vivo.
Brandt, Ingvar,   +3 more
core  

Inhibition of Hedgehog/Gli1 signaling blocks p,p′-DDE-induced DLD1 cell proliferation.

open access: yes, 2014
After DLD1 cells were transfected with control siRNA or Gli1 siRNA, followed by treating with p,p′-DDE (10−9 M) for 96 h, (A) Protein levels of Gli1, c-Myc and cyclin D1 were examined by western blotting. α-tubulin was used as a control.
Weiping Liu (47182)   +5 more
core   +1 more source

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