Residues of p,p′-DDE and mercury in lake trout as a function of age
Archives of Environmental Contamination and Toxicology, 1992Lake trout (Salvelinus namaycush) of known age from 1 to 12 years were taken from Cayuga Lake in central New York State in 1991 and p,p'-DDE and mercury were determined in their flesh. The concentrations of p,p'-DDE and mercury increased significantly (p less than 0.001) with increasing age of the fish.
W H, Gutenmann +4 more
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Transplacental and Lactational Transfer of p,p′-DDE in Sprague–Dawley Rats
Toxicology and Applied Pharmacology, 1999p,p'-DDE (hereafter DDE), a persistent metabolite of p,p'-DDT, is a widespread environmental contaminant that can induce antiandrogenic developmental effects in rats. Quantitative measurements of the transfer of DDE from pregnant or lactating dams to the fetus or suckling neonate were performed, and physiologically based pharmacokinetic (PBPK) models ...
L, You +5 more
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Induction of hepatic aromatase by p,p′-DDE in adult male rats
Molecular and Cellular Endocrinology, 20011,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE, DDE) is a stable metabolite of the pesticide DDT and a persistent environmental pollutant. Earlier reports have demonstrated that DDE is an endocrine-active compound capable of affecting early-stage sexual differentiation in male rats.
L, You +4 more
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Circulating levels of p,p'-DDE are related to prevalent hypertension in the elderly
Environmental Research, 2014Polychlorinated biphenyls (PCBs) and dioxin given to experimental animals increase the blood pressure. We therefore investigated if circulating levels of persistent organic pollutants (POPs) were related to hypertension in a population-based sample of men and women.One thousand and sixteen subjects aged 70 years were investigated in the Prospective ...
Lind, PM +4 more
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Adipose tissue concentrations of p,p′-DDE and the risk for endometrial cancer
Gynecologic Oncology, 2004To evaluate in a case-control study possible risk of endometrial cancer associated with environmental endocrine disruptors.We analyzed the adipose tissue concentrations of polychlorinated biphenyls, hexachlorobenzene (HCB), p,p'-dichlorodiphenyl-dichloroethylene (p,p'-DDE), chlordanes, and polybrominated biphenyls in 76 cases with endometrial cancer ...
Lennart, Hardell +7 more
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Breastfeeding and concentrations of HCB and p,p′-DDE at the age of 1 year
Environmental Research, 2005Exposure to organochlorine compounds (OCs) occurs both in utero and through breastfeeding. Levels of hexachlorobenzene (HCB) in the cord serum of newborns from a population located in the vicinity of an electrochemical factory in Spain are among the highest ever reported. We aimed to assess the degree of breast milk contamination in this population and
Núria, Ribas-Fitó +5 more
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Levels of p , p ′-DDE in Liver of Predatory Birds from Calabria, Italy
Bulletin of Environmental Contamination and Toxicology, 2002In the present study, the levels of OCs in the liver of predatory birds were evaluated. Liver samples were collected from 80 birds (9 different species) found dead or dying in the territory of Calabria region of Southern Italy from 1993 to 1997. Collected data were compared to data already available regarding the OCs contamination in predatory birds ...
DE LIGUORO, MARCO +4 more
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Persistent DDT metabolite p,p'–DDE is a potent androgen receptor antagonist
Nature, 1995The increase in the number of reports of abnormalities in male sex development in wildlife and humans coincided with the introduction of 'oestrogenic' chemicals such as DDT (1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane) into the environment. Although these phenotypic alterations are thought to be mediated by the oestrogen receptor, they are also ...
W R, Kelce +5 more
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Influence of plant–earthworm interactions on SOM chemistry and p,p′-DDE bioaccumulation
Chemosphere, 2011Laboratory experiments assessed how bioaccumulation of weathered p,p'-DDE from soil and humic acid (HA) chemistry are affected by interactions between the plants Cucurbita pepo ssp. pepo and ssp. ovifera and the earthworms Eisenia fetida, Lumbricus terrestris, and Apporectodea caliginosa. Total organochlorine phytoextraction by ssp.
Jason W, Kelsey +3 more
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Structure of phenolic metabolites of p,p′-DDE in rat, wild seal and guillemot
Nature, 1975WE recently described the isolation and characterisation of metabolites of polychlorinated biphenyls from field-collected samples, that is faeces from guillemots and seals1. In addition to the PCB metabolites—hydroxychlorobiphenyls—we unexpectedly found two compounds which after treatment with diazomethane gave mass spectra consistent with p,p′-DDE (1 ...
G, Sundstrom, B, Jansson, S, Jensen
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