Results 91 to 100 of about 466,613 (249)

Xenograft of human pancreas tumor cell lines in zebrafish embryos and their response to drugs [PDF]

, 2017
Traballo fin de mestrado (UDC.CIE). Bioloxía molecular, celular e xenética. Curso 2016/2017[Resumen] La incidencia actual del cáncer sobre la población general hace necesaria una investigación cada vez mayor con el fin de dotar de calidad de vida a las ...
Lodeiro Aranda, Marina
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Technical difficulties and success of endoscopic retrograde colangiopancreatography in a group of patients

Medisur, 2011
Background: Endoscopic Retrograde Cholangiopancreatography has been effective in the diagnosis and treatment of diseases of the biliopancreatic system.
Pedro Juan Vázquez González, Marcos Félix Osorio Pagola, Gustavo Becerra Terón, Mayelin González Pérez, Pedro Juan Barrios Fuentes, Denis Monzón Vega, Mabel Vega Galindo   +6 more
doaj  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

El Síndrome Metabólico como factor de riesgo para el desarrollo de Diabetes Mellitus de Tipo 2 [PDF]

, 2015
El Síndrome Metabólico (SM), de gran prevalencia en la población mundial, se define como un conjunto de factores fisiológicos, bioquímicos, clínicos y metabólicos, que se encuentran interconectados (hipertensión, obesidad abdominal, dislipemia ...
Álvarez Rodríguez, Virginia
core  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Apoptosis de las células Beta del páncreas durante la diabetes de tipo I

Revista de la Facultad de Medicina, 2006
La diabetes de tipo 1 se produce como resultado de la destrucción de las células ß del páncreas. Durante la progresión de la enfermedad las células se ven crónicamente atacadas por un infiltrado inflamatorio de tipo autoinmune con gran cantidad de ...
Camila Manrique, Diego G. Silva
doaj  

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Trasplante pancreático [PDF]

, 2006
Diabetes mellitus is a health concern of the first order, given the high level of associated morbidity and mortality. The objective, in order to slow down the advance of its complications before they become irreversible, is based on correct
Montiel, C. (Custodia), Pardo, F. (Fernando), Pastor, C. (Carlos), Rotellar, F. (Fernando), Valenti, V. (Víctor), Álvarez-Cienfuegos, J. (Javier)   +5 more
core  

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source