Results 91 to 100 of about 471,910 (249)

Análisis descriptivo de resultados de resecciones pancreáticas mayores y factores pronósticos de morbimortalidad en un hospital de tercer nivel [PDF]

open access: yes, 2019
El cáncer de páncreas (CP) es la cuarta causa principal de muertes relacionadas con el cáncer, y tiene una de las tasas más bajas de supervivencia relativa (9,3%) a 5 años entre todos los tipos de cáncer (1).
Valle López, Sergio
core  

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach   +4 more
wiley   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett   +7 more
wiley   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian   +10 more
wiley   +1 more source

Apoptosis de las células Beta del páncreas durante la diabetes de tipo I

open access: yesRevista de la Facultad de Medicina, 2006
La diabetes de tipo 1 se produce como resultado de la destrucción de las células ß del páncreas. Durante la progresión de la enfermedad las células se ven crónicamente atacadas por un infiltrado inflamatorio de tipo autoinmune con gran cantidad de ...
Camila Manrique, Diego G. Silva
doaj  

Científicos asturianos hallan un nuevo método para detectar el cáncer de páncreas [PDF]

open access: yes, 2016
Artículo periodístico de divulgación científica escrito por Marcos Palicio.Peer ...
Fernández, Agustín F., Fraga, Mario F.
core  

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

open access: yesAdvanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn   +14 more
wiley   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura   +4 more
wiley   +1 more source

Traumatismos de páncreas: diagnóstico y tratamiento Pancreatic trauma: diagnosis and treatment

open access: yesRevista Colombiana de Cirugía, 2008
Los traumatismos de páncreas son infrecuentes; representan, aproximadamente, el 4% de las lesiones abdominales pero conllevan una tasa de morbimortalidad significativa, razón por la cual es primordial su reconocimiento y tratamiento precoz.
Patrizio Petrone   +4 more
doaj  

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