Results 151 to 160 of about 449,060 (250)

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

open access: yesAdvanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao   +7 more
wiley   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu   +13 more
wiley   +1 more source

Pancreas Transplantation for Recipients with Type 2 Diabetes Mellitus: Results of an International Survey. [PDF]

open access: yesTransplant Direct
Fridell JA   +15 more
europepmc   +1 more source

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

open access: yesAdvanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler   +4 more
wiley   +1 more source

Laparoscopic Local Resection via Duodenotomy for Cystic Heterotopic Pancreas Involving the Gastroduodenal Junction: A Case Report. [PDF]

open access: yesSurg Case Rep
Gakuhara A   +10 more
europepmc   +1 more source

Carcinomas metácronos de colon y páncreas

open access: yes, 1996
Two patients, one male and one fema/e, wereoperated upan successively of right colon cancerand of pancreas head, the former, and of cephalicpancreas carcinoma and of the rectum, the latter.The tour tumors were resected onco/ogical/y.Fol/owing the ...
Navarrete, Héctor   +3 more
core  

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Seudoquistes de páncreas: Directivas terapéuticas

open access: yes, 1971
The paper analyzes the definition of this disease, followed by consideration of the surgical tactics employed and a discusston on the valué of the different methods for treating pancreatic pseudocysts according to their size, location and canalicular ...
Larre Borges, Uruguay, Delgado, Bolivar
core  

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