Results 21 to 30 of about 471,910 (249)
Levels of IGFBP-1, 3 and 7 in human serum induced by alcohol consumption, NAFLD and dual insult
Annals of HepatologyIntroduction and Objectives: Alcoholic liver and non-alcoholic liver disease causes liver disease. Dual damage has been gaining great relevance. Insulin growth factor binding proteins (IGFBPs) regulate the signaling pathways of IGF; IGFBP-3 have emerged ...
Abigail Hernandez-Barragan +12 more
doaj +1 more source
Regulation of TGF-β1, 2, and 3 and IL-10 at systemic level in chronic liver disease
Annals of HepatologyIntroduction and Objectives: Chronic liver disease (CLD) is considered an important health problem worldwide. The production of IL-10 regulated the hepatic inflammation.
Marisela Hernandez-Santillan +12 more
doaj +1 more source
The role of oxidative stress in the development of alcoholic liver disease
Revista de Gastroenterología de México (English Edition), 2014 Background: Alcohol is the most accepted addictive substance worldwide and its consumption is related to multiple health, economic, and social problems.
M. Galicia-Moreno, G. Gutiérrez-Reyes
doaj +1 more source
APLICACIÓN DE UN INSTRUMENTO PARA EVALUAR EL NIVEL DE CONOCIMIENTOS EN PACIENTES CON DIABETES MELLITUS TIPO 2 SOBRE SU ENFERMEDAD, ANTES Y DESPUÉS DE UNA ORIENTACIÓN NUTRICIONAL EN EL H.G.Z No. 71 DEL IMSS EN EL PERIODO FEBRERO- AGOSTO 2014 [PDF]
, 2015 La Diabetes es una enfermedad crónica que aparece cuando el páncreas no produce insulina suficiente o cuando el organismo no utiliza eficazmente la insulina que produce.
FLORES HERNÁNDEZ, LAURA +1 more
core
Hacia la concentración de la cirugía oncológica digestiva: cambios en la activad, las técnicas y los resultados [PDF]
, 2017 Objetivo: se examinaron los cambios en actividad, técnicas quirúrgicas y resultados del proceso de concentración de la cirugía oncológica digestiva compleja entre 2005-2012 en relación a 1996-2000.
Borràs Andrés, Josep Maria +7 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Esplenopancreatectomia corporocaudal videoasistida por tumor de Frantz
Cirugía Paraguaya, 2020 El tumor pseudopapilar sólido del páncreas es poco frecuente de bajo potencial maligno. Se presenta el caso de una mujer de 17 años de edad acude a consulta por dolor abdominal de inicio insidioso de moderada intensidad; sin hallazgossignificativos en el
Dayhana Duarte +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Hiperinsulinismo endógeno diagnosticado como epilepsia
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2017 El insulinoma es la neoplasia endocrina más común del páncreas, 90% de ellos son benignos, su incidencia es de 4 por 1 millón de personas al año y representa el 1% al 2% de todas las neoplasias pancreáticas.
Alejandro Pinzón Tovar +1 more
doaj +1 more source