Results 41 to 50 of about 834,783 (289)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Estudo de caso [PDF]

open access: yes, 2010
História Clínica: Um paciente com história de diversas lesões nos membros inferiores foi intervencionado em ambos os pés, onde realizou uma tenossinovectomia dos peroneais com reparação de ruptura desses tendões (ao pé direito em 2006 sendo ...
Dias, Olga
core   +2 more sources

The Tardivo protocol: A breakthrough in preventing diabetic foot amputations

open access: yesJournal of Photochemistry and Photobiology
Diabetes Mellitus (DM) affects over 460 million people worldwide, and its poor control often leads to severe circulatory damage and infected ulcers. These complications, exacerbated by bacterial resistance and impaired perfusion, drastically reduce the ...
JP Tardivo, MS Baptista
doaj   +1 more source

Efeitos da espuma de feltro no tratamento do pé diabético: revisão sistemática com metanálise

open access: yesRevista da Escola de Enfermagem da USP, 2020
RESUMO Objetivo: Avaliar os efeitos da espuma de feltro no tratamento da úlcera plantar do pé diabético. Método: Revisão sistemática, com metanálise. As buscas foram realizadas na Cochrane Library, PubMed, CINAHL, Science Direct, Web of Science, SCOPUS,
Jayana Castelo Branco Cavalcante de Meneses   +5 more
doaj   +2 more sources

Contribution de la Robinia pseudoacacia pour la Valorisation des Feuillus Précieux: Un Cas d'Étude [PDF]

open access: yes, 2010
Em 1998, no âmbito do projecto PRAXIS XXI – 3/3.2/Flor/2127/95, foi estabelecido um ensaio de consociação de folhosas nobres: cerejeira, carvalho e castanheiro com a espécie acessória, robínia, numa série substitutiva, em Vimioso (Latitude 41º34'12''N ...
Lopes, Domingos   +3 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Fabry-Pérot interference enhanced surface plasmon resonance sensor

open access: yesSPIE Proceedings, 2010
A Fabry-Perot interference enhanced surface plasmon resonance (SPR) sensor was designed and analyzed numerically. In this paper, a micro-fluidic channel with two parallel interfaces formed on the metal film of an angular-interrogated SPR sensor was employed.
Sung, Ming-Je   +2 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Cuidado de los pies en usuarios que viven con diabetes en el estado de México: bases para la sistematización de la asistencia de enfermería [PDF]

open access: yes, 2010
Trata-se de um estudo do tipo descritivo transversal com abordagem quantitativa, realizado numa população de 20 usuários do estado do México em 2009, com o objetivo de identificar as informações do paciente em relação ao cuidado com o pé diabético ...
GARCIA REZA, CLEOTILDE   +1 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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