Results 31 to 40 of about 151 (73)
Strategy for modular assembly of tetravalent, multispecific antibodies
Abstract Multispecific, multivalent antibodies (Abs) are a burgeoning class of drugs that dramatically expand the pharmacological repertoire beyond traditional therapeutic Abs. Here, we present a simple, modular approach to developing multispecific, multivalent Abs based on a Fab‐phage library with a single light chain.
Evan Mallette +12 more
wiley +1 more source
‘A simple outgrowth of the democracy’: Women's Suffrage, Democracy, and the Third Reform Act
Abstract The 1884 Reform Act was a landmark in the history of British democracy, creating almost three million voters and bringing farm labourers, miners, and shipworkers cascading onto the register. Yet 1884 was also a moment of democratic exclusion.
Robert Saunders
wiley +1 more source
Creb3l1 Overexpression Improves Flexor Tendon Repair in Aged Rats
Aging impairs flexor tendon repair, with aged tendons showing reduced Col1a1 and Sparc expression and compromised mechanical properties. The transcription factor Creb3l1 binds both gene promoters and drives their expression; its overexpression restores Col1a1 and Sparc levels and improves the gliding function, healing strength, and elastic modulus of ...
Qian Qian Yang +4 more
wiley +1 more source
Diagnosticiranje kongenitalnega sifilisa pri novorojenčku: pregled literature in prikaz primera
Sifilis je kronična sistemska okužba, ki jo povzroča spiroheta T. pallidum. Metoda izbire za postavitev diagnoze so serološki testi, in sicer testi za treponemska in testi za netreponemska protitelesa. Nezdravljena okužba v času nosečnosti lahko povzroči
Hana Bešić +3 more
doaj +1 more source
ABSTRACT I defend the non‐instrumentalist thesis that every adult member of a political society has a pro tanto fundamental moral right to an equal democratic say in determining the content of the laws to which she is subject. I begin by giving an account of an important kind of servility that has received only glancing notice in philosophical ...
Shruta Swarup
wiley +1 more source
Janez Musek: Nova psihološka teorija vrednot
Z novo knjigo Janeka Muska je naša knjižna produkcija bogatejša za kakovostno znanstveno monografijo o vrednotah. Knjiga z naslovom Nova psihološka teorija vrednot, ki je izšla pri založbi Educy in Inštitutu za psihologijo osebnosti, 2000, je plod ...
Tanja Šulak
doaj +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Analiza vodenja poterminske nosečnosti v Sloveniji v letu 2012
Uvod: V literaturi je poterminska nosečnost različno opredeljena, prav tako tudi ukrepi v zvezi z njo. Podaljšanje nosečnosti preko 41. tedna nosečnosti prinaša dodatna tveganja za plod, zato se v tem primeru pogosto sprejme odločitev o indukciji poroda.
Klavdija Obreza +2 more
doaj +1 more source
ABSTRACT Some subtypes of head and neck squamous cell carcinoma (HNSCC) exhibit aggressive progression and poor prognosis, underscoring the need for novel therapeutic targets. While procollagen‐lysine, 2‐oxoglutarate 5‐dioxygenase 1 (PLOD1) is implicated in tumour collagen remodelling, its functional role and regulatory mechanisms in HNSCC remain ...
Yan‐Ling Wu +6 more
wiley +1 more source
Delo za Slovar slovenskega knjižnega jezika
V članku je podan pregled dela v Inštitutu za slovenski jezik Frana Ramovša v zadnjih petdesetih letih. Glavna naloga Inštituta je bila zbiranje gradiva in priprava slovarja sodobnega slovenskega jezika.
Milena Hajnšek-Holz
doaj +1 more source

