Results 91 to 100 of about 42,945,397 (252)
Comparative nonlinear analysis of a RC 2D frame soil-pile interaction [PDF]
Građevinski Materijali i Konstrukcije, 2018 Comparative non-linear static (NSA) and non-linear dynamic analyses (NDA) of 2D frames (as parts of skeletal 3D structures) of RC buildings founded on piles are presented in this paper.
Folić Boris, Folić Radomir
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
CivilEngThis study presents the nonlinear seismic analysis of a large-scale suspension bridge under multiple sequential earthquake records. A detailed 3D finite element model is developed in SAP2000, incorporating CFST pylons, a composite deck, and a main cable ...
Lydia Konstantina Georgiou Zonara +1 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Response of Monopiles Under Lateral Loading By Centrifuge Modeling
نشریه مهندسی دریا, 2016 One of the most common methods to analyze and design monopiles under lateral load is load-displacement curves, particularly the p-y curves, at different locations of the structure.
Hamid Reza Khodaei +2 more
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
P-Y Curves for Rigid Walls Retaining Granular Soil [PDF]
, 2020 Salah Sadek Mounir Mabsout Jacques Harb Fadi Hage ChehadeThe mobilization of lateral stresses behind retaining walls constitutes a typical soil structure interaction problem particularly under cyclic loading conditions.
El Chiti, Imad
core
Statistical Evaluation of API P-Y Curve Model for Offshore Piles in Cohesionless Soils
ModellingPile foundations are widely used to support offshore wind turbines. While the p-y curve method is adopted for analysis of pile–soil interactions in popular design specifications, including the American Petroleum Institute (API), its accuracy remains ...
Peiyuan Lin, Xun Yuan, Tong Liu
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source