Results 1 to 10 of about 2,429 (203)

Surface modification with P-aminohippuric acid on biogenic apatite (fish bones) particles [PDF]

Marine Science and Technology Bulletin, 2014
The aim of this study with fish bones as a waste in fish processing is to investigate whether they can provide more efficient and multi-functional materials by chemical modification.
Evren Tan, Bayram Kizilkaya, Nail Ucyol, Hasan Basri Ormanci, Ayhan Oral   +4 more
doaj   +6 more sources

Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy [PDF]

Advances in Pharmacological Sciences, 2011
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli.
Chiao-Shih Tseng, Shih-Ming Chen, Shu-Chen Chien, Kuang-Yang Hsu   +3 more
doaj   +2 more sources

A combined pig model to determine the net absorption of volatile fatty acids in the large intestine under different levels of crude fiber

Animal Models and Experimental Medicine, 2023
Background This study aimed to develop a combined model to quantify the net absorption of volatile fatty acids (VFA) in the large intestine (LI) of pigs. Methods Fifteen female growing pigs (Duroc × Large White × Landrace) were ranked by body weight (30 ±
Shengjun Zhao, Liangkang Lv, Taotao Wu, Zhi Feng, Qiang Li, Long Lei, Zhengya Liu, Hui Zhang, Ying Ren   +8 more
doaj   +2 more sources

Simultaneous Measurement of Glomerular Filtration Rate, Effective Renal Plasma Flow and Tubular Secretion in Different Poultry Species by Single Intravenous Bolus of Iohexol and Para-Aminohippuric Acid [PDF]

Animals, 2020
The aim of the current study was to investigate the simultaneous measurement of plasma p-aminohippuric acid (PAH) clearance as a potential marker to assess effective renal plasma flow (eRPF) and tubular secretion (TS), and the plasma clearance of iohexol
Lenka Stroobant, Siska Croubels, Laura Dhondt, Joske Millecam, Siegrid De De Baere, Elke Gasthuys, Joachim Morrens, Gunther Antonissen   +7 more
doaj   +4 more sources

Effects of Combination Treatment on Renal Endothelial Function in Type 2 Diabetes Mellitus [PDF]

Kidney International Reports
Introduction: Recently, we demonstrated that a combination therapy with empagliflozin and linagliptin (E+L) in patients with type 2 diabetes mellitus (T2DM) induce changes in renal hemodynamics.
Merve Günes-Altan, Agnes Bosch, Kristina Striepe, Mario Schiffer, Roland E. Schmieder, Dennis Kannenkeril   +5 more
doaj   +2 more sources

Unveiling mechanisms underlying kidney function changes during sex hormone therapy [PDF]

The Journal of Clinical Investigation
BACKGROUND Men with chronic kidney disease (CKD) experience faster kidney function decline than women. Studies in individuals undergoing sex hormone therapy suggest a role for sex hormones, as estimated glomerular filtration rate (eGFR) increases with ...
Sarah A. van Eeghen, Laura Pyle, Phoom Narongkiatikhun, Ye Ji Choi, Wassim Obeid, Chirag R. Parikh, Taryn G. Vosters, Irene G.M. van Valkengoed, Merle M. Krebber, Daan J. Touw, Martin den Heijer, Petter Bjornstad, Daniël H. van Raalte, Natalie J. Nokoff   +13 more
doaj   +2 more sources

Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women

npj Breast Cancer, 2021
Known modifiable risk factors account for a small fraction of premenopausal breast cancers. We investigated associations between pre-diagnostic circulating amino acid and amino acid-related metabolites (N = 207) and risk of breast cancer among ...
Oana A. Zeleznik, Raji Balasubramanian, Yibai Zhao, Lisa Frueh, Sarah Jeanfavre, Julian Avila-Pacheco, Clary B. Clish, Shelley S. Tworoger, A. Heather Eliassen   +8 more
doaj   +1 more source

Antiviral Activity of Acetylsalicylic Acid against Bunyamwera Virus in Cell Culture

Viruses, 2023
The Bunyavirales order is a large group of RNA viruses that includes important pathogens for humans, animals and plants. With high-throughput screening of clinically tested compounds we have looked for potential inhibitors of the endonuclease domain of a
Sara Yolanda Fernández-Sánchez, José P. Cerón-Carrasco, Cristina Risco, Isabel Fernández de Castro   +3 more
doaj   +1 more source

Net Portal Appearance of Amino Acids in Iberian and Landrace Pigs Fed Different Protein Content in the Diet

Animals, 2023
Iberian pigs have low rates of muscle protein deposition compared with modern breeds. Differences in net portal appearance (NPA) of amino acids (AA) might partially explain that. NPA of AA was measured in six Iberian and six Landrace gilts (28 kg) fitted
Manuel Lachica, José Miguel Rodríguez-López, Lucrecia González-Valero, Ignacio Fernández-Fígares   +3 more
doaj   +1 more source

Oral Proteasomal Inhibitors Ixazomib, Oprozomib, and Delanzomib Upregulate the Function of Organic Anion Transporter 3 (OAT3): Implications in OAT3-Mediated Drug-Drug Interactions

Pharmaceutics, 2021
Organic anion transporter 3 (OAT3) is mainly expressed at the basolateral membrane of kidney proximal tubules, and is involved in the renal elimination of various kinds of important drugs, potentially affecting drug efficacy or toxicity.
Yunzhou Fan, Zhengxuan Liang, Jinghui Zhang, Guofeng You   +3 more
doaj   +1 more source