Results 121 to 130 of about 1,406 (193)
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Simultaneous determination of p-aminohippuric acid, acetyl-p-aminohippuric acid and iothalamate in human plasma and urine by high-performance liquid chromatography

Journal of Chromatography B: Biomedical Sciences and Applications, 1998
A sensitive and specific high-performance liquid chromatographic assay was developed for the simultaneous determination of p-aminohippuric acid (PAH), acetyl-p-aminohippuric acid (aPAH), and iothalamate in human plasma and urine. Plasma samples were prepared by protein precipitation with acetonitrile followed by evaporation, reconstitution in mobile ...
T C, Dowling, R F, Frye, M A, Zemaitis
openaire   +2 more sources

The metabolism of p-aminohippuric acid and p-acetylamino-hippuric acid

Clinica Chimica Acta, 1967
Abstract p-Aminohippuric acid or p-acetylaminohippuric acid administered to patients orally instead of intravenously as a method to determine their kidney function was found to give erroneously low clearance values. It was found that these compounds lost the glycine moiety by hydrolysis in the alimentary tract and were converted in the tissues to ...
W.C. Hülsmann, L.W.Statius Van Eps
openaire   +1 more source

Synthesis of p-aminohippuric acid analog and its labeling by technetium-99m

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1989
A procedure is described for the synthesis of p-[(bisacarboxymethyl)aminomethyl carbamino] hippuric acid (PAHIDA). The compound was identified by i.r. and NMR spectroscopy. A lyophilized complex was prepared and labeled with 99mTc. The purity of the preparation is better than 98%. The stability of the 99mTc-PAHIDA complex is achieved 8 h after labeling.
B, Zmbova   +5 more
openaire   +3 more sources

[Changes in intestinal absorption of p-aminohippuric acid in ancylostomaisis].

open access: closedArchivio italiano di scienze mediche tropicali e di parassitologia, 1968
F, Loschiavo, D, Gallo
openaire   +2 more sources

Clinical investigations of 99mTc–p-aminohippuric acid as a new renal agent

Nuclear Medicine Communications, 2009
99mTc-p-aminohippuric acid (PAH) is a new radiopharmaceutical rapidly secreted by the kidneys in a manner consistent with tubular secretion. A comparative study of renal scintigraphy and clearance with 99mTc-PAH, diethylene triamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine (MAG,) was performed.99mTc-PAH was prepared from a lyophilized kit ...
Emilija, Jaksić   +7 more
openaire   +2 more sources

P-aminohippuric acid(PAH) accumulation impairment after treatment with segment-specific nephrotoxicants

Toxicology Letters, 1998
Hexachloro-1:3-butadiene (HCBD) and potassium dichromate (Cr6+) are chemicals toxic for the pars recta and the pars convoluta, respectively. PAH accumulation takes place in the basolateral membrane of the proximal tubule and its impairment is a sign of damage of the membrane.
TREVISAN, ANDREA   +5 more
openaire   +2 more sources

p-Aminohippuric acid transport into brush border vesicles isolated from flounder kidney

American Journal of Physiology-Renal Physiology, 1979
p-Aminohippuric acid (PAH) transport was investigated in brush border vesicles isolated from renal proximal tubules of the winter flounder. Three characteristics of carrier-mediated transport were demonstrated: 1) unlabeled PAH inhibited the uptake of [3H]PAH; 2)[3H]PAH efflux from the vesicles was stimulated in the presence of unlabeled PAH in the ...
Eveloff, J., Kinne, R., Kinter, W.
openaire   +3 more sources

Comparison of renal prostaglandin and p-aminohippuric acid transport processes

American Journal of Physiology-Renal Physiology, 1978
L Z, Bito, R A, Baroody
openaire   +2 more sources

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