Transporter-Mediated Interactions Between Uremic Toxins and Drugs: A Hidden Driver of Toxicity in Chronic Kidney Disease. [PDF]
Int J Mol SciSpicher P +6 more
europepmc +1 more source
Central nervous system permeation of ibuprofen, ketoprofen and indomethacin: in vivo and in situ studies in rats and clinical studies in children (Ibuprofeenin, ketoprofeenin ja indometasiinin kulkeutuminen keskushermostoon: in vivo ja in situ tutkimuksia rotilla ja kliinisiä tutkimuksia lapsilla) [PDF]
Mannila, Anne
core
Related searches:
Quantitation of P-Aminohippuric Acid and N-Acetyl-P-Aminohippuric Acid from Blood by HPLC
Journal of Liquid Chromatography, 1981Abstract P-aminohippuric acid, N-acetyl-p-aminohippuric acid, and p-aminobenzoic acid can be separated by a reverse-phase, isocratic high-pressure liquid chromatographic procedure in less than 4 minutes. The eluent is 10 mM sodium phosphate buffer, pH 3.5, containing 30% methanol.
D. J. Meerdink +3 more
openaire +1 more source
Abstract20 pigs weighing 21–124 kg were used to determine the clearance of PAH, N4‐acetylated PAH and PAHtotal, and for determination of acetylation of PAH and de‐acetylation of N4‐acetylated PAH in the kidney. By examining blood samples taken from a. renalis and v.
N. Gyrd‐Hansen, Folke Rasmussen
openaire +1 more source
99Tcm-p-aminohippuric acid as a new renal agent
Nuclear Medicine Communications, 199999Tcm-p-aminohippuric acid (99Tcm-PAH) is a new renal radiopharmaceutical prepared from a lyophilized kit by the addition of sodium pertechnetate (Na99TcmO4). Each vial contains PAH, the calcium trisodium salt of diethylenetriamine pentaacetic acid (CaNa3DTPA) and stannous chloride (SnCl2.2H2O) in an inert atmosphere. It is a stable radiopharmaceutical
D, Djokić +5 more
openaire +2 more sources
Technetium-99m Labeled p-Aminohippuric Acid Analogues: Renal Function Agents
Journal of Pharmaceutical Sciences, 1989A number of p-aminohippuric acid analogues were synthesized in order to develop clinically useful 99mTc-labeled radiopharmaceuticals for evaluation of renal function measurements. Stable 99mTc-labeled complexes were formed at pH 5.7 using a Sn(II) reduction method with all derivatives.
Z, Zhang +4 more
openaire +2 more sources
p-Aminohippuric acid accumulation in kidney slices in cloudy swelling
Experientia, 1959L'incorporazione dell'acidop-aminoippurico nelle sezioni di rene di ratto e diminuita nel rigonfiamento torbido provocato dal trattamento parenterale con tossina stafilococcioa, con dinitrofenolo o con tiroxina. Tutti questi trattamenti provocano anche dissociazione delle fosforilazioni dalle ossidazioni.
B, FIDA, G C, BIAGGINI, M U, DIANZANI
openaire +2 more sources
A sensitive and specific high-performance liquid chromatographic assay was developed for the simultaneous determination of p-aminohippuric acid (PAH), acetyl-p-aminohippuric acid (aPAH), and iothalamate in human plasma and urine. Plasma samples were prepared by protein precipitation with acetonitrile followed by evaporation, reconstitution in mobile ...
T C, Dowling, R F, Frye, M A, Zemaitis
openaire +2 more sources
The metabolism of p-aminohippuric acid and p-acetylamino-hippuric acid
Clinica Chimica Acta, 1967Abstract p-Aminohippuric acid or p-acetylaminohippuric acid administered to patients orally instead of intravenously as a method to determine their kidney function was found to give erroneously low clearance values. It was found that these compounds lost the glycine moiety by hydrolysis in the alimentary tract and were converted in the tissues to ...
W.C. Hülsmann, L.W.Statius Van Eps
openaire +1 more source