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Synthesis of p-aminohippuric acid analog and its labeling by technetium-99m

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1989
A procedure is described for the synthesis of p-[(bisacarboxymethyl)aminomethyl carbamino] hippuric acid (PAHIDA). The compound was identified by i.r. and NMR spectroscopy. A lyophilized complex was prepared and labeled with 99mTc. The purity of the preparation is better than 98%. The stability of the 99mTc-PAHIDA complex is achieved 8 h after labeling.
B, Zmbova   +5 more
openaire   +3 more sources

Clinical investigations of 99mTc–p-aminohippuric acid as a new renal agent

Nuclear Medicine Communications, 2009
99mTc-p-aminohippuric acid (PAH) is a new radiopharmaceutical rapidly secreted by the kidneys in a manner consistent with tubular secretion. A comparative study of renal scintigraphy and clearance with 99mTc-PAH, diethylene triamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine (MAG,) was performed.99mTc-PAH was prepared from a lyophilized kit ...
Emilija, Jaksić   +7 more
openaire   +2 more sources

P-aminohippuric acid(PAH) accumulation impairment after treatment with segment-specific nephrotoxicants

Toxicology Letters, 1998
Hexachloro-1:3-butadiene (HCBD) and potassium dichromate (Cr6+) are chemicals toxic for the pars recta and the pars convoluta, respectively. PAH accumulation takes place in the basolateral membrane of the proximal tubule and its impairment is a sign of damage of the membrane.
TREVISAN, ANDREA   +5 more
openaire   +2 more sources

p-Aminohippuric acid transport into brush border vesicles isolated from flounder kidney

American Journal of Physiology-Renal Physiology, 1979
p-Aminohippuric acid (PAH) transport was investigated in brush border vesicles isolated from renal proximal tubules of the winter flounder. Three characteristics of carrier-mediated transport were demonstrated: 1) unlabeled PAH inhibited the uptake of [3H]PAH; 2)[3H]PAH efflux from the vesicles was stimulated in the presence of unlabeled PAH in the ...
Eveloff, J., Kinne, R., Kinter, W.
openaire   +3 more sources

Comparison of renal prostaglandin and p-aminohippuric acid transport processes

American Journal of Physiology-Renal Physiology, 1978
L Z, Bito, R A, Baroody
openaire   +2 more sources

Renal Clearance of P-Aminohippuric Acid and Inulin in Dairy Cattle

Journal of Animal Science, 1968
F L, Mangelson   +3 more
openaire   +2 more sources

Tumour fatty acid metabolism in the context of therapy resistance and obesity

Nature Reviews Cancer, 2021
Andrew J Hoy   +2 more
exaly  

Tc-99(m)-p-aminohippuric acid as a new renal agent

1999
Tc-99(m)-p-aminohippuric acid (Tc-99(m)-PAH) is a new renal radiopharmaceutical prepared from a lyophilized kit by the addition of sodium pertechnetate ((NaTcO4)-Tc-99-O-m. Each vial contains PAH, the calcium trisodium salt of diethylenetriamine pentaacetic acid (CaNa(3)DTPA) and stannous chloride (SnCl2. 2H(2)O) in an inert atmosphere.
Đokić, Divna Đ.   +5 more
openaire   +1 more source

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