Results 31 to 40 of about 2,429 (203)
Pharmacology Research &Perspectives, Volume 10, Issue 3, June 2022., 2022 Mechanistic static pharmacokinetic models predict that CYP450 inhibition and induction are unlikely for fenfluramine or its major metabolite norfenfluramine at doses used for seizure reduction (0.2−0.7 mg/kg/day). These results suggest minimal drug‐drug interaction perpetrator potential for either fenfluramine or norfenfluramine.
Parthena Martin +5 more
wiley +1 more source
Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. [PDF]
PLoS ONE, 2015 Obesity is an important risk factor for the development of chronic kidney disease. One of the major factors involved in the pathogenesis of obesity-associated kidney disease is glomerular hyperfiltration.
Boris Zingerman +7 more
doaj +1 more source
HPLC estimation of iothalamate to measure glomerular filtration rate in humans [PDF]
, 2016 Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and urine.
Ashraf, Syed Salman +4 more
core +1 more source
Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites [PDF]
PeerJ, 2018 Most valuable cured products from Iberian pigs come from pure bred animals raised for a final grazing-fattening period where pigs eat mainly acorns, a low protein energy rich fruit.
Ignacio Fernández-Fígares +3 more
doaj +2 more sources
The synthesis of some acylglycines and related oxazolones [PDF]
, 1960 No description ...
Acheson, R M +3 more
core +1 more source
Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]
, 2017 Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan +6 more
core +3 more sources
System Identification of the Low-Dose Kinetics of p-Aminohippuric Acid [PDF]
cclm, 1995 The renal clearance of p-aminohippuric acid, due to tubular secretion in addition to glomerular filtration, can only be determined by kinetic experiments. Maximal information can be gained from observed temporal marker concentration profiles by fitting dynamic mathematical models of the processes involved, such as absorption, distribution, and ...
Estelberger, Willibald +8 more
openaire +3 more sources
Animal, 2018 In nutrition studies, para-aminohippuric acid (PAH) is a marker frequently used to measure blood flow in pigs, which is essential for estimating portal-drained viscera (PDV) flux of nutrients.
I. Fernández-Fígares +3 more
doaj +1 more source
Marine Drugs, 2017 This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto +6 more
doaj +1 more source
Active Mammary Excretion of N4-Acetylated p-Aminohippuric Acid*) [PDF]
Acta Veterinaria Scandinavica, 1969 Different excretion patterns were observed for p-amino- hippuric acid and its acetylated metabolite in mammary excretion experiments in goats and cows. The excretion of p-aminohippuric acid conformed to passive diffusion of the non-protein bound and un-ionized fraction (Rasmussen 1958, 1966) as described by Miller et al. (1967).
openaire +2 more sources