Results 41 to 50 of about 1,205 (134)
Effects of patent foramen ovale in migraine: a metabolomics‐based study
The Journal of Physiology, Volume 603, Issue 4, Page 809-835, 15 February 2025.Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong +15 more
wiley +1 more source
The distribution of p-aminohippuric acid in rat kidney slices. I. Tubular localization
Kidney International, 1973 The distribution of p-aminohippuric acid in rat kidney slices. I. Tubular localization. Tubular localization of tritiated p-aminohippuric acid (PAH) was determined by section freeze-dry autoradiography in rat renal cortical slices in vitro. Autoradiographs were also prepared from tissue after incubation in tritiated alpha-aminoisobutyric acid (AIB ...
Richard P. Wedeen, Barry Weiner
openaire +3 more sources
Frontiers in Pharmacology, 2019 Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of ...
Joske Millecam +10 more
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Chemical assay of p-aminohippuric acid simplified by use of dimethylaminocinnamaldehyde in ethanol.
Clinical Chemistry, 1988 Abstract We have developed a new and simple method of p-aminohippuric acid determination by use of dimethylaminocinnamaldehyde (DACA). It differs from previous methods using DACA in that the reaction is carried out in ethanol rather than in dilute acid. This results in deeper and more stable color development.
Lewis B. Schwartz +2 more
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Journal of Food Science, Volume 89, Issue 12, Page 10134-10151, December 2024.Abstract Olive oil polyphenol hydroxytyrosol (HT) significantly repairs intestinal barrier function, but its absorption in the stomach and small intestine is limited. The metabolites of unabsorbed HT that reach the colon are crucial, yet their effects on colonic microbiota and intestinal barrier repair remain unclear.
Yuqing Song +7 more
wiley +1 more source
The change of p-aminohippuric acid disposition kinetics accompanied by growth in mice.
Journal of Pharmacobio-Dynamics, 1985 The change of disposition kinetics for p-aminohippuric acid (PAH) was studied following intravenous administration of p-[glycyl-1-14C]aminohippuric acid to 1-day-old, 1-week-old, 3-week-old and 8-week-old mice. The expiratory excretion of 14CO2 in 24 h following the administration was almost negligible in 1-day-old and 1-week-old mice in contrast to 3 ...
Junji Hirate +3 more
openaire +4 more sources
The distribution of p-aminohippuric acid in rat kidney slices. II. Depth of uptake
Kidney International, 1973 The distribution of p-aminohippuric acid in rat kidney slices. II. Depth of uptake. Section freeze-dry autoradiography was used to measure the depth to which concentrative uptake of PAH-3H occurs within rat renal cortical slices in vitro under conditions of varied incubation time, temperature and PAH medium concentration.
Richard P. Wedeen, Barry Weiner
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Maturation of p-Aminohippuric Acid Transport in the Developing Rabbit Kidney: Interrelationships of the Individual Components [PDF]
Pediatric Research, 1978 The excretion of both endogenous organic (aryl) acids, such as benzoic acid, and exogenous ones, such as p-aminohippuric acid (PAH), penicillin, and furosemide, is reduced in the human neonate and other immature animals. The unique developmental pattern of aryl acid transport in immature rabbit kidney cortex slices is produced by the interrelationships
Robson Am +9 more
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Determination of p-aminohippuric acid with β-cyclodextrin sensitized fluorescence spectrometry
RSC Advances, 2016 Sensitive spectrofluorometric and HPLC with fluorescence detection methods have been developed for detection and determination of para-aminohippuric acid (a marker used for estimating effective renal plasma flow) in the presence of β-cyclodextrin.
Rashed H. Alremeithi +4 more
openaire +2 more sources
Animal, 2018 In nutrition studies, para-aminohippuric acid (PAH) is a marker frequently used to measure blood flow in pigs, which is essential for estimating portal-drained viscera (PDV) flux of nutrients.
I. Fernández-Fígares +3 more
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