Results 71 to 80 of about 940,927 (266)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Benchmarking the Retrieval of Biomass in Boreal Forests Using P-Band SAR Backscatter with Multi-Temporal C- and L-Band Observations

open access: yesRemote Sensing, 2019
The planned launch of a spaceborne P-band radar mission and the availability of C- and L-band data from several spaceborne missions suggest investigating the complementarity of C-, L-, and P-band backscatter with respect to the retrieval of forest above ...
Oliver Cartus   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

FAIR fission track analysis with geochron@home [PDF]

open access: yesGeochronology
Fission track thermochronology is based on the visual analysis of optical images. This visual process is prone to observer bias. Fission track datasets are currently reported as numerical summary tables. The interpretation of these tables requires a high
P. Vermeesch   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

TROPICAL FOREST BIOMASS AND ITS RELATIONSHIP WITH P - BAND SAR DATA

open access: yesRevista Brasileira de Cartografia, 2009
The objective of this research is to show the potential of P-band polarimetric SAR images to define the space of attributes of primary and regenerating forest and also to estimate aerial biomass of such formations. The approach used was the analysis of
João Roberto dos Santos   +6 more
doaj  

Upgrading of the L-P Band Cryogenic Receiver of the Sardinia Radio Telescope: A Feasibility Study. [PDF]

open access: yesSensors (Basel), 2022
Ladu A   +6 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Topological Superfluid in P-band Optical Lattice

open access: yes, 2011
4.2 pages, 4 ...
Wu, Ya-Jie   +3 more
openaire   +2 more sources

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