Results 181 to 190 of about 441,089 (308)

Wide‐/Narrow‐Bandgap Heterojunction for High Performance Differential Photodetector with Tunable Response

open access: yesAdvanced Science, EarlyView.
A differential photodetector is developed by applying the unique characteristics of a wide‐/narrow‐bandgap semiconductor heterojunction. The mechanism based on band alignment enables high detectivity and high bandwidth with tunable photoresponse.
Ziyang Ren   +11 more
wiley   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

open access: yesAdvanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang   +16 more
wiley   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

open access: yesAdvanced Science, EarlyView.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan   +7 more
wiley   +1 more source

The fiber of persistent homology for trees. [PDF]

open access: yesJ Appl Comput Topol
Beers D, Leygonie J.
europepmc   +1 more source

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