Results 11 to 20 of about 48,325 (261)

Integration of P-hub Location Problem and 3M Supply Chain [PDF]

International Journal of Supply and Operations Management, 2019
The present study proposes an integrated model for hub location problem in a Multi-location, Multi-period, Multi-commodity (3M), three echelon supply chain. The problem is formulated as a mixed integer programming model and solved using GAMS software. As
M.B. Fakhrzad, Amir Shafiei Alavijeh., H. Hossaini Nasab, A. Mostafaeipour   +3 more
doaj   +3 more sources

Abstract 070: Door in‐door out time for stroke thrombectomy transfers in a large hub‐and‐spoke network

Stroke: Vascular and Interventional Neurology, 2023
Introduction The mantra ‘time is brain’ cannot be overstated for patients suffering from acute ischemic stroke. This is especially true for those with large vessel occlusions (LVO) requiring transfer to an endovascular thrombectomy (EVT) capable center ...
Rashid A. Ahmed, Joyce A. McIntyre, Thabele M. Leslie‐Mazwi, Alvin S. Das, Adam A. Dmytriw, Joshua A. Hirsch, James D. Rabinov, Omer Doron, Christopher J. Stapleton, Aneesh B. Singhal, Natalia S. Rost, Aman B. Patel, Robert W. Regenhardt   +12 more
doaj   +1 more source

Direct to Angio‐Suite Large Vessel Occlusion Stroke Transfers Achieve Faster Arrival‐to‐Puncture Times and Improved Outcomes

Stroke: Vascular and Interventional Neurology, 2022
Background For patients with large vessel occlusion (LVO) stroke, time to treatment with endovascular thrombectomy is crucial to prevent infarction and improve outcomes. We sought to evaluate the hub arrival‐to‐puncture times and outcomes for transferred
Robert W. Regenhardt, Joseph A. Rosenthal, Adam A. Dmytriw, Justin E. Vranic, Anna K. Bonkhoff, Martin Bretzner, Joshua A. Hirsch, James D. Rabinov, Christopher J. Stapleton, Aman B. Patel, Aneesh B. Singhal, Natalia S. Rost, Thabele M. Leslie‐Mazwi, Mark R. Etherton   +13 more
doaj   +1 more source

Intravenous Thrombolysis by Telestroke in the 3- to 4.5-h Time Window

Frontiers in Neurology, 2021
Background: While intravenous thrombolysis (IVT) in ischemic stroke can be safely applied in telestroke networks within 3 h from symptom onset, there is a lack of evidence for safety in the expanded 3- to 4. 5-h time window.
Erik Simon, Matin Forghani, Andrij Abramyuk, Simon Winzer, Claudia Wojciechowski, Lars-Peder Pallesen, Timo Siepmann, Heinz Reichmann, Volker Puetz, Kristian Barlinn, Jessica Barlinn   +10 more
doaj   +1 more source

Upgrading Uncapacitated Multiple Allocation P-Hub‎ ‎Median‎ ‎Problem‎ ‎Using‎ ‎Benders Decomposition Algorithm [PDF]

Mathematics Interdisciplinary Research
‎The Hub Location Problem (HLP) is a significant problem in combinatorial optimization consisting of two main components‎: ‎location and network design‎.
Ali Hosseinzadeh, Ardeshir Dolati
doaj   +1 more source

Characterizing Reasons for Stroke Thrombectomy Ineligibility Among Potential Candidates Transferred in a Hub‐and‐Spoke Network

Stroke: Vascular and Interventional Neurology, 2022
Background Access to endovascular thrombectomy (EVT) is relatively limited. Hub‐and‐spoke networks seek to transfer appropriate large‐vessel occlusion stroke candidates to EVT‐capable hubs.
Robert W. Regenhardt, Amine Awad, Andrew W. Kraft, Joseph A. Rosenthal, Adam A. Dmytriw, Justin E. Vranic, Anna K. Bonkhoff, Martin Bretzner, Mark R. Etherton, Joshua A. Hirsch, James D. Rabinov, Aneesh B. Singhal, Natalia S. Rost, Christopher J. Stapleton, Thabele M. Leslie‐Mazwi, Aman B. Patel   +15 more
doaj   +1 more source

Spoke‐Administered Thrombolysis Improves Large‐Vessel Occlusion Early Recanalization: The Real‐World Experience of a Large Academic Hub‐and‐Spoke Telestroke Network

Stroke: Vascular and Interventional Neurology, 2023
Background Intravenous thrombolysis (IVT) before mechanical thrombectomy (MT) for large‐vessel occlusion (LVO) stroke is increasingly controversial. Recent trials suggest MT without IVT is reasonable for patients presenting directly to MT‐capable “hub ...
Andrew W. Kraft, Robert W. Regenhardt, Amine Awad, Joseph A. Rosenthal, Adam A. Dmytriw, Justin E. Vranic, Anna K. Bonkhoff, Martin Bretzner, Joshua A. Hirsch, James D. Rabinov, Christopher J. Stapleton, Lee H. Schwamm, Aneesh B. Singhal, Natalia S. Rost, Thabele M. Leslie‐Mazwi, Aman B. Patel   +15 more
doaj   +1 more source

Star p-hub median problem with modular arc capacities [PDF]

Computers & Operations Research, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +5 more sources

Abstract 1122‐000031: Reasons Thrombectomy Candidates Become Ineligible After Transfer for Treatment in a Hub‐And‐Spoke Telestroke Model

Stroke: Vascular and Interventional Neurology, 2021
Introduction: The care of emergent large vessel occlusion (ELVO) stroke patients has been revolutionized by endovascular thrombectomy (EVT). Given its robust efficacy, it is crucial to optimize delivery to eligible patients. Within hub‐and‐spoke hospital
Robert W Regenhardt, Amine Awad, Andrew W Kraft, Joseph A Rosenthal, Adam A Dmytriw, Justin E Vranic, Anna K Bonkhoff, Martin Bretzner, Joshua A Hirsch, James D Rabinov, Christopher J Stapleton, Mark R Etherton, Aneesh B Singhal, Natalia S Rost, Thabele M Leslie‐Mazwi, Aman B Patel   +15 more
doaj   +1 more source

Identification of LOX as a candidate prognostic biomarker in Glioblastoma multiforme

Translational Oncology, 2023
Background: Glioblastoma multiforme (GBM) is the most malignant type of glioma. GBM tumors grow rapidly, have a high degree of malignancy, and are characterized by a fast disease progression. Unfortunately, there is a lack of effective treatments.
Erheng Liu, Wenjuan Li, Li-peng Jian, Shi Yin, Shuaifeng Yang, Heng Zhao, Wei Huang, Yongfa Zhang, Hu Zhou   +8 more
doaj   +1 more source