Results 131 to 140 of about 21,096,303 (314)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
P-values from statistical analysis of matrix comparison data.
, 2016 P-values from statistical analysis of matrix comparison data.
Michael E. Bose (133005) +8 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Efficient Computation of a Canonical Form for a Generalized P-matrix
, 2012 We use recent results on algorithms for Markov decision problems to show that a canonical form for a generalized P-matrix can be computed, in some important cases, by a strongly polynomial algorithm.
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
On the connectedness of numerical range of matrix polynomials
, 1998 An investigation on nonconnectedness of numerical range for monic matrix polynomials L(λ) is undertaking here. The distribution of eigenvalues of L(λ) to the components of numerical range and some other algebraic properties are also ...
Maroulas, J. +5 more
core +1 more source
Changes in Spo0A~P pulsing frequency control biofilm matrix deactivation.
PLoS Computational BiologyUnder starvation conditions, B. subtilis survives by differentiating into one of two cell types: biofilm matrix-producing cells or sporulating cells. These two cell-differentiation pathways are activated by the same phosphorylated transcription factor ...
Cristina S D Palma +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
A new kind of $A_{\p}$-matrix for mixed graphs
Nikiforov\cite{nikiforov2017merging} introduced the concept of the $A_{\p}$-matrix as a convex linear combination of a graph's adjacency matrix and its diagonal matrix of vertex degrees. In this paper, we introduce a new variant of the $A_{\p}$-matrix, which is a linear combination of the Hermitian adjacency matrix of the second kind, $H^{\om}$, and ...
Sharma, Piyush, Kumar, Ravinder
openaire +2 more sources