Results 111 to 120 of about 27,923,169 (310)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Crystal structure and photochemical property of 1,8-bis(p-tolylthio)pyrene, C30H22S2
Zeitschrift für Kristallographie - New Crystal Structures, 2019 C30H22S2, triclinic, P1̄ (no. 2), a = 7.604(4) Å, b = 11.556(5) Å, c = 13.090(7) Å, α = 93.964(8)°, β = 93.209(8)°, γ = 90.619(9)°, V = 1145.7(10) Å3, Z = 2, Rgt(F) = 0.0497, wRref(F2) = 0.1295, T = 296(2) K.
Bin Wen, Li-Hua Xu, Na Liu, Zhong-Hai Ni
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 2011 Updated irregularly; Began in 2007; ceased in 2009.; Title from home page (publisher's Web site, viewed May 25, 2011).; Harvested from the web on 5/25/11Official website of the Connecticut Office of Ombudsman for Property Rights.
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Discover Applied SciencesAccurately predicting molecular properties is crucial in chemistry and materials science, as it facilitates faster discovery, minimizes experimental costs, and guides rational molecular design. While traditional quantum chemistry approaches remain widely
Jamshaid Ul Rahamn +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Developing a retail property syndication performance index
, 2002 With property syndicates accounting for 12.3% of property investment in Australia in 1998-99 (Property Investment Research, 1999), Table 1 presents a profile of property syndication in Australia at June 2000 (Property Investment Research, 2000a).
Newell, Graeme, Acheampong, Peter
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source