Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Integrating Molecular Semantics and Three-Dimensional Geometry for Critical Property Prediction: A Multimodal GNN-BERT Framework. [PDF]
Wang B, Lv Z, Ning N, Zhang Y, Zhang J.
europepmc +1 more source
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Physics-Informed Machine Learning for Sustainable Alloy Design: Toward a Recyclable Unified Q&P Steel. [PDF]
Wei X +7 more
europepmc +1 more source
APPLICATION OF WEAKLY P PROPERTIES GIVING INFINITELY MANY NEW CHARACTERIZATIONS OF T1 AND T2 SPACES
openaire +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Research on intellectual property rights and legal liability definition of artificial intelligence-assisted pediatric disease diagnosis system. [PDF]
Yang Z, Yang W.
europepmc +1 more source
Correction: Huang et al. Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK. <i>Int. J. Mol. Sci.</i> 2017, <i>18</i>, 1063. [PDF]
Huang Q, Wang T, Yang L, Wang HY.
europepmc +1 more source
Dimensional analysis as a tool for biofilm comparative analysis: bridging the interdisciplinary divides. [PDF]
Middleton CM, Jones A-AD.
europepmc +1 more source

