Results 191 to 200 of about 208,012 (229)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Structured Process Informed by Data, Evidence and Research (SPIDER) framework: Eight legs of success for running projects in primary care practices. [PDF]

Can Fam Physician
Greiver M, Dahrouge S, Manca DP, Singer AG, Jean-Xavier C, Kosowan L, Pathiraja H, Grandy M, Lussier MT, Aubrey-Bassler K, O'Brien T, Authier M, Dev R, Garies S.   +13 more
europepmc   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

The effect of complex training on strength, counter movement jump and change of direction skills in female junior table tennis players. [PDF]

Sci Rep
Sun R, Qu H, Zhang Y, Wang H.
europepmc   +1 more source

Effects of different exercise levels on serum trace element concentrations. [PDF]

Sci Rep
Xue Y, Zhang L, Fei F, Yang J.
europepmc   +1 more source

Understanding Population Health Management Practices Among Family Medicine Residency Programs. [PDF]

Fam Med
Carek SM, Brown C, Neutze D, Emerson J, Shaffer M, Ewing A, Carek PJ.   +6 more
europepmc   +1 more source

Health Literacy Recommendations for Digital Mental Health Treatments. [PDF]

Health Lit Res Pract
Fisher AC, Rezwan A, Muscat DM, Ayre J, Bisby M, Hathway T, Choi I, Titov N, Dear BF.   +8 more
europepmc   +1 more source

Coded Aperture Optimization in X-Ray Computed Tomography via Sparse Covariance Matrix Estimation. [PDF]

Sensors (Basel)
Jiang Y, Mao T, Zhou J, Zhao Q, Yin J, Yi X, Wu H.   +6 more
europepmc   +1 more source