Results 221 to 230 of about 40,520,431 (232)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Temporal vision adaptation and restoration in achromatopsia. [PDF]

iScience
McKyton A, Bick A, Elul D, Abulafia R, Marks Ohana D, Nahmany E, Banin E, Levin N.   +7 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Characterising Thermotolerance Traits and Their Acclimation Potential in Two Important Forestry Species of Eucalyptus. [PDF]

Physiol Plant
Matimati I, Hovenden MJ, Blackman CJ.
europepmc   +1 more source

PACSIN2 regulates mercaptopurine cytotoxicity and cellular biomechanics through Rac1 modulation in intestinal epithelial cells. [PDF]

Front Pharmacol
Norbedo A, Zudeh G, Fiducioso D, Senigagliesi B, Parisse P, Casalis L, Decorti G, Lucafò M, Stocco G.   +8 more
europepmc   +1 more source

Immediate Effects of Walking Training With Elastic Ankle Support Devices on Walking and Mobility of Ambulatory Individuals With Stroke. [PDF]

Ann Rehabil Med
Chanata T, Amatachaya S, Nithiatthawanon T, Wannapakhe J, Chanwised W, Wiyanad A, Thaweewanakij T, Namwong W.   +7 more
europepmc   +1 more source

Automated Multienzyme Digestion Workflows for Confident Characterization of Challenging Posttranslational Modifications in Therapeutic Antibodies by LC-MS/MS. [PDF]

Rapid Commun Mass Spectrom
Eskesen NS, Leblanc Y, Lempereur J, Ørgaard M, Madzharova E, Sloth TM, Krabbe S, Rebak AK, André M, Jensen PF, Kristensen DB.   +10 more
europepmc   +1 more source

Generative AI as a cognitive support tool in early-stage design ideation: A human-AI co-ideation experiment. [PDF]

PLoS One
Lin YJ.
europepmc   +1 more source

Provide Medical Conditions Counseling [PDF]

Provide Medical Conditions Counseling
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