IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu +9 more
wiley +1 more source
Factors Influencing Indoor Xylene Concentrations and Biomarkers in the General Population Based on the 2020-2021 KNHANES. [PDF]
Kim MJ, Park S, Kim A, Sung JH.
europepmc +1 more source
Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source
Influence of different urine preservation methods and addition of preservatives on quantitative detection of 24-h urinary protein. [PDF]
Bao X, Sun X, Geng H, Yuan X.
europepmc +1 more source
The Ammoxidation of p-Xylene over Fe(or Ni, Co)-Mo Binary Catalysts
Kyosuke Sato, Jokichi KATO, Nobuto Ohta
openalex +1 more source
Understanding the p-Xylene Formation Mechanism from Dimethylfuran and Ethanol [PDF]
Kostetskyy, P +4 more
core
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu +10 more
wiley +1 more source
Impact of ototoxic agents and noise exposure on hearing loss among healthcare personnel in a medical university: a cross-sectional analytical study. [PDF]
Choosong T +3 more
europepmc +1 more source
Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira +18 more
wiley +1 more source
Detection and Proinflammatory Effects of BTEX within the Human Atherosclerotic Plaque. [PDF]
Marfella R +30 more
europepmc +1 more source

