Results 231 to 240 of about 3,383,900 (322)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Predictive value of serum chitinase 3-like 1 for dysfunctional autogenous arteriovenous fistulas in patients with chronic kidney disease stage G5. [PDF]

Clinics (Sao Paulo)
Lin YW, Zhang Q, Xu YS, Qu T.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Femoral radiographic indices for pre-operative osteoporosis screening in postmenopausal female patients undergoing total hip arthroplasty for osteoarthritis. [PDF]

PLoS One
Nishi M, Yoshikawa Y, Usui Y, Nishida H, Nakamura S, Tashiro K, Kudo Y.   +6 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A Signature of Typical MRI Features and Time-Intensity Curve Achieves Accurate Diagnosis of Distensible Orbital Venous Malformation. [PDF]

Invest Ophthalmol Vis Sci
Li Y, Tang Y, Fu Y, Cui J, Song X, Wang Y, Jia R.   +6 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

A diagnostic model for NTM disease in HIV-positive patients: a machine learning-based analysis with novel inflammatory markers. [PDF]

Front Immunol
Li L, Shi C, Liu X, Li W, Luo Y, Zhang H, Wang G, Zhao Y, Huang Y, Yang J, Yang J, Li S, Shen L.   +12 more
europepmc   +1 more source

Determination of p-y Curves for Bucket Foundations in Silt and Sand Using Finite Element Modelling

, 2017
Vinojan Vethanayagam, Lars Bo Ibsen
openalex   +1 more source