Results 21 to 30 of about 26,768 (221)
Electrophysiological and morphological alteration in the visual pathway of children with attention-deficit/hyperactivity disorder [PDF]
IntroductionAttention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Optical Coherence Tomography (OCT) and Visual evoked potentials (VEP) are common non-invasive diagnostic techniques ...
Zixuan Huang +12 more
doaj +2 more sources
Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100 [PDF]
We show that galactomannan, a polysaccharide consisting of a mannose backbone with galactose side groups present on the cell wall of several fungi, induces a reprogramming of the inflammatory response in human macrophages through dectin-1 receptor.
Víctor Toledano +9 more
doaj +2 more sources
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility [PDF]
NF-κB2/p100 (p100) is an inhibitor of κB (IκB) protein that is partially degraded to produce the NF-κB2/p52 (p52) transcription factor. Heterozygous NFKB2 mutations cause a human syndrome of immunodeficiency and autoimmunity, but whether autoimmunity ...
Daley, SR +24 more
core +1 more source
Individuals attention bias in perceived loneliness: an ERP study
Purpose Loneliness refers to an unhappy or depressed negative emotion in which individuals feel poor intimacy in quantity or quality in current social relationships. It is not only common among the elderly, but also widely among young adults.
Xiao Du, Yi Tang, Yuhao Jiang, Yin Tian
doaj +1 more source
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
variants reveal a p100-degradation threshold that defines autoimmune susceptibility [PDF]
NF-κB2/p100 (p100) is an inhibitor of κB (IκB) protein that is partially degraded to produce the NF-κB2/p52 (p52) transcription factor. Heterozygous NFKB2 mutations cause a human syndrome of immunodeficiency and autoimmunity, but whether autoimmunity ...
Matthew C. Cook +58 more
core +1 more source
Helicobacter pylori infection represents a major risk factor for the development of gastric diseases and gastric cancer. The capability of H. pylori to inject the virulence factor cytotoxin-associated gene A (CagA) depends on a type IV secretion system ...
Gunter Maubach +3 more
doaj +1 more source
Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52
Summary: The eradication of HIV infection is difficult to achieve because of stable viral reservoirs. Here, we show that crotonylation enhances AZD5582-induced noncanonical NF-κB (ncNF-κB) signaling, further augmenting HIV latency reversal in Jurkat and ...
Dajiang Li +10 more
doaj +1 more source
The Value of VR-PVEP in Objective Evaluation of Monocular Refractive Visual Impairment [PDF]
Objective To study the virtual reality-pattern visual evoked potential (VR-PVEP) P100 waveform characteristics of monocular visual impairment with different impaired degrees under simultaneous binocular perception and monocular stimulations.
Hong-xia HAO, Jie-min CHEN, Rong-rong WANG, Xiao-ying YU, Meng WANG, Zhi-lu ZHOU, Yan-liang SHENG, Wen-tao XIA
doaj +1 more source

