Results 21 to 30 of about 26,768 (221)

Electrophysiological and morphological alteration in the visual pathway of children with attention-deficit/hyperactivity disorder [PDF]

open access: yesFrontiers in Psychiatry
IntroductionAttention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Optical Coherence Tomography (OCT) and Visual evoked potentials (VEP) are common non-invasive diagnostic techniques ...
Zixuan Huang   +12 more
doaj   +2 more sources

Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100 [PDF]

open access: yesMediators of Inflammation, 2015
We show that galactomannan, a polysaccharide consisting of a mannose backbone with galactose side groups present on the cell wall of several fungi, induces a reprogramming of the inflammatory response in human macrophages through dectin-1 receptor.
Víctor Toledano   +9 more
doaj   +2 more sources

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility [PDF]

open access: yes, 2021
NF-κB2/p100 (p100) is an inhibitor of κB (IκB) protein that is partially degraded to produce the NF-κB2/p52 (p52) transcription factor. Heterozygous NFKB2 mutations cause a human syndrome of immunodeficiency and autoimmunity, but whether autoimmunity ...
Daley, SR   +24 more
core   +1 more source

Individuals attention bias in perceived loneliness: an ERP study

open access: yesBrain-Apparatus Communication, 2022
Purpose Loneliness refers to an unhappy or depressed negative emotion in which individuals feel poor intimacy in quantity or quality in current social relationships. It is not only common among the elderly, but also widely among young adults.
Xiao Du, Yi Tang, Yuhao Jiang, Yin Tian
doaj   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

variants reveal a p100-degradation threshold that defines autoimmune susceptibility [PDF]

open access: yes, 2020
NF-κB2/p100 (p100) is an inhibitor of κB (IκB) protein that is partially degraded to produce the NF-κB2/p52 (p52) transcription factor. Heterozygous NFKB2 mutations cause a human syndrome of immunodeficiency and autoimmunity, but whether autoimmunity ...
Matthew C. Cook   +58 more
core   +1 more source

CEACAMs interaction with Helicobacter pylori HopQ supports the type 4 secretion system-dependent activation of non-canonical NF-κB

open access: yesInternational Journal of Medical Microbiology, 2020
Helicobacter pylori infection represents a major risk factor for the development of gastric diseases and gastric cancer. The capability of H. pylori to inject the virulence factor cytotoxin-associated gene A (CagA) depends on a type IV secretion system ...
Gunter Maubach   +3 more
doaj   +1 more source

Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52

open access: yesiScience, 2022
Summary: The eradication of HIV infection is difficult to achieve because of stable viral reservoirs. Here, we show that crotonylation enhances AZD5582-induced noncanonical NF-κB (ncNF-κB) signaling, further augmenting HIV latency reversal in Jurkat and ...
Dajiang Li   +10 more
doaj   +1 more source

p100 WT

open access: yes, 2018
P100 ...
YUZHU HOU (7007771)
core   +2 more sources

The Value of VR-PVEP in Objective Evaluation of Monocular Refractive Visual Impairment [PDF]

open access: yesFayixue Zazhi, 2023
Objective To study the virtual reality-pattern visual evoked potential (VR-PVEP) P100 waveform characteristics of monocular visual impairment with different impaired degrees under simultaneous binocular perception and monocular stimulations.
Hong-xia HAO, Jie-min CHEN, Rong-rong WANG, Xiao-ying YU, Meng WANG, Zhi-lu ZHOU, Yan-liang SHENG, Wen-tao XIA
doaj   +1 more source

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