Results 51 to 60 of about 26,768 (221)

Complement Activation Linked to Type II Interferon Signaling in Still Disease

Arthritis &Rheumatology, EarlyView.
Objective Still disease (SD) is an autoinflammatory syndrome characterized by innate immune dysregulation. Although complement can drive inflammation, its involvement in SD remains to be defined. Thus, we aimed to assess complement activation in SD. Methods Complement was assessed using transcriptomic, proteomic, and in vitro approaches. RNA sequencing
Freya M. C. H. Huijsmans, Tabea Thalheim, Alejandra Bodelón, Greta Rogani, Lyanne J. P. M. Sijbers, Remco G. A. Erkens, Aafke de Ligt, Rianne Scholman, Aron Brinker, Gisella B. Beretta, Nienke M. Ter Haar, Thomas Vogl, Johannes Roth, Trang T. Duong, Sytze de Roock, Joost F. Swart, Deborah A. Marshall, Susanne M. Benseler, Rae S. M. Yeung, Christoph Kessel, Sebastiaan J. Vastert, Emely L. Verweyen, Jorg van Loosdregt, on behalf of the UCAN CAN‐DU/UCAN CURE Consortia and the One Child Every Child Initiative, Adam Huber, Bianca Lang, Chelsea DeCoste, Elizabeth Stringer, Suzanne Ramsey, Alan Rosenberg, Kate Neufeld, Mehul Jariwala, Tristan Kerr, Alexander Mosoiu, Alisa Rachlis, Amy Xu, Arthur Cheng, Brenleigh Jebb, Brian Feldman, Bruno Pereira, Deborah Levy, Dilan Dissanayake, Elizaveta Limenis, Evelyn Rozenblyum, Harper Cheng, Jennifer Ji Young Lee, Lynn Spiegel, Rayfel Schneider, Ronald Laxer, Ruud Verstegen, Shirley Tse, Andrea Human, David Cabral, Herman Tam, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Mercedes Chan, Ross Petty, Tommy Gerschman, Annet van Royen‐Kerkhof, Berent Prakken, Erika Van Nieuwenhove, Marc Jansen, Nico Wulffraat, Ciarán Duffy, Nadia Luca, Roman Jurencak, Tala El Tal, Claire LeBlanc, Gaëlle Chédeville, Piya Lahiry, Rosie Scuccimarri, Sarah Campillo, Clare Hutchinson, Daniah Basodan, Dax G Rumsey, Hon Yan Ng, Jeanine McColl, Lillian Lim, Tara McGrath, Danielle Brinkman, Petra Hissink Muller, Elizabeth Legger, Wineke Armbrust, Ellen Schatorje, Esther Hoppenreijs, Elodie Boudes, Gillian Currie, Heinrike Schmeling, Muhammed Dhalla, Nicole Johnson, Paivi Miettunen, Ravneet Sran, Rebeka Stevenson, Erkan Demirkaya, Jonathan Park, Roberta Berard, Giske Biesbroek, Mariken Gruppen, Gordon Soon, Joseph Cafazzo, Liane Heale, Michelle Batthish, Tania Cellucci, Lily Lim, Maarten IJzerman, Marinka Twilt, Marleen Verkaaik, Philomine van Pelt, Sylvia Kamphuis, Michelle Kip, Nicholas Blanchette, Paul Dancey, Regina de Geus   +115 more
wiley   +1 more source

Visual Evoked Potential: A Tool for Detection of Preretinopathy and Prognostication in Diabetes [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Diabetic Retinopathy (DR) is a common complication of Diabetes Mellitus (DM) that affects retinal blood vessels. It is the leading cause of blindness in the age group of 20 to 74 years despite the fact that visual loss due to DM may be ...
G Krishnachandra Prasad, Anjamparuthikal Aboobekar Haris   +1 more
doaj   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Updated facility‐level inventory and LCIA of the public electricity grid in Ontario, Canada

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract As the composition of Ontario's electricity grid will change over time, it is important to have a comprehensive understanding of the environmental impacts of Ontario's electricity grid as it stands today. However, publicly available information on impacts of Ontario's electricity grid is available only in aggregate from government sources.
Jamie Rose, Thomas A. Adams II, Giancarlo Dalle Ave   +2 more
wiley   +1 more source

The Role of PRMT5/MEP50 in p100-centric κBsome Assembly [PDF]

, 2017
It is well known that nearly half of all NF-κB subunits are inhibited by the precursor inhibitors, p100 and p105, whereas the other half are by classical IκBs (IκBα, IκBβ and IκBε). Our laboratory showed, through experiments done in vivo, that inhibition
Gu, Boqing
core  

P100 and N200.

, 2014
A) P100 component at electrodes O1 and O2 and B) N200 at electrodes P9 and P10 for both conditions (walker, scramble) separately. Typically developing controls are indicated by solid lines and ADHD by dashed lines.
Michael Siniatchkin (475526), Anne Kröger (521271), Christine M. Freitag (184876), Tomasz Jarczok (521274), Christoph Krick (521273), Stephan Bender (157984), Katharina Hof (521272)   +6 more
core   +1 more source

NF-kappa B2/p100 induces Bcl-2 expression [PDF]

, 2003
peer reviewedThe NF-kappaB2/p100 and bcl-3 genes are involved in chromosomal translocations described in chronic lymphocytic leukemias (CLL) and non-Hodgkin's lymphomas, and nuclear factor kappaB (NF-kappaB) protects cancer cells against apoptosis ...
Bentires-Alj, Mohamed, Viatour, Patrick, Chariot, Alain, de Leval, Laurence, Bours, Vincent, Deregowski, Valérie, Merville, Marie-Paule   +6 more
core   +1 more source

Update of the P100-1 Concrete Provisions [PDF]

Mathematical Modelling in Civil Engineering, 2014
Abstract In an effort to improve the harmonization of the Romanian design codes with the Eurocodes, the revision of the Seismic Design Code, P100-1, started in April 2010 and ended in September 2013. The main issues addressed during the revision process are presented in this paper.
openaire   +1 more source

Stabilization of RelB Requires Multidomain Interactions with p100/p52 [PDF]

Journal of Biological Chemistry, 2008
The NF-kappaB family member RelB has many properties not shared by other family members such as restricted subunit association and lack of regulation by the classical IkappaB proteins. We show that the protein level of RelB is significantly reduced in the absence of p100 and reduced even more when both p100 and p105 are absent.
Amanda J, Fusco, Olga V, Savinova, Rashmi, Talwar, Jeffrey D, Kearns, Alexander, Hoffmann, Gourisankar, Ghosh   +5 more
openaire   +2 more sources

Altered cortical synchronization in photosensitive idiopathic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto, Cecilia Steinwurzel, Francesco Turco, Enrica Bonanni, Roberto Cantello, Gionata Strigaro   +5 more
wiley   +1 more source