Results 61 to 70 of about 171,284 (274)

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Evaluation of novel cardiovascular risk calculators in patients with rheumatoid arthritis

Journal of Rheumatic Diseases
Objective: CT-P13, a biosimilar of infliximab, is widely used for treating ankylosing spondylitis (AS). However, the formation of anti-drug antibodies (ADAs) can reduce its efficacy.
Dionicio Angel Galarza-Delgado, Valeria Gonzalez-Gonzalez, Natalia Guajardo-Jauregui, Jesus Alberto Cardenas-de la Garza, Rosa Icela Arvizu-Rivera, Maria Fernanda Elizondo-Benitez, Andrea Lizbeth Guajardo-Aldaco, Jose Ramon Azpiri-Lopez, Iris Jazmin Colunga-Pedraza   +8 more
doaj   +1 more source

Electroexcitation of nucleon resonances at Q^2=0.65 GeV/c^2 from a combined analysis of single- and double-pion electroproduction data

, 2005
Data on single- and double-charged pion electroproduction off protons are successfully described in the second and third nucleon resonance regions with common N* photocouplings. The analysis was carried out using separate isobar models for both reactions.
B. S. Ishkhanov, G. V. Fedotov, I. G. Aznauryan, M. Bellis, V. D. Burkert, V. D. Burkert, V. I. Mokeev, V. Mokeev   +7 more
core   +1 more source

Electromagnetic properties of strange baryons in a relativistic quark model [PDF]

, 2007
We present some of our results for the electromagnetic properties of excited Σ hyperons, computed within the framework of the Bonn constituent-quark model, which is based on the Bethe-Salpeter approach.
D. Merten, Ph. Forcrand de, S. Taylor, T. Cauteren Van, T. Cauteren Van, U. Löring, W.-M. Yao   +6 more
core   +2 more sources

Genetic Abnormalities and Clinical Management of Fetal Genitourinary System Anomalies in Eastern China

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT To investigate the correlation between genetic abnormalities and fetal genitourinary (GU) anomalies in Eastern China and to provide assistance for the clinical management of fetuses with different types of GU anomalies. Five hundred forty‐five fetuses with GU anomalies were enrolled, undergoing karyotyping, copy number variation sequencing ...
Jie Liang, Jiebin Wu, Lin Zhang, Yunmeng Qi, Yi Wang, Xu Cao, Jingfang Zhai   +6 more
wiley   +1 more source

A novel nitrogenous coumarin: The promising antiviral therapy against white spot syndrome virus in the culture of shrimp seedlings

Aquaculture Reports
White spot disease (WSD), attributed to the white spot syndrome virus (WSSV), represents a substantial danger to the international shrimp sector, resulting in considerable losses in both production and economic terms. Nevertheless, there are currently no
Huan Wang, Xu Zhang, Lei Liu, Li-Peng Shan   +3 more
doaj   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Pharmacokinetic comparison of subcutaneously administered CT‐P13 (biosimilar of infliximab) via autoinjector and pre‐filled syringe in healthy participants

Clinical and Translational Science
CT‐P13, a biosimilar of infliximab, is used to treat inflammatory diseases that arise from immune system complications, resulting in excessive and persistent inflammation.
Ye Chan Park, Jae Hoon Kim, Sung Hyun Kim, Ju Hyun Lee, Jang Hee Hong, Jin‐Gyu Jung, Jung Sunwoo   +6 more
doaj   +1 more source

Molecular Profiling of Genes Associated With Methylphenidate Pathway Therapy and Discovery of New Variants in Amazonian Amerindian Populations

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos, Tatiane Carinta de Souza, Kaio Evandro Cardoso Aguiar, Ana Caroline Alves da Costa, Natasha Monte, Juliana Carla Gomes Rodrigues, Giovanna Gilioli da Costa Nunes, Rita de Cássia Calderaro Coelho, Ândrea Ribeiro‐dos‐Santos, André Maurício Ribeiro dos Santos, Sandro José de Souza, Sidney Emanuel Batista dos Santos, Rommel Mario Rodriguez Burbano, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +14 more
wiley   +1 more source

Comparison of endoscopic healing and durability between infliximab originator and CT-P13 in pediatric patients with inflammatory bowel disease

Frontiers in Immunology
Background and aimsFavourable clinical data were published on the efficacy of CT-P13, the first biosimilar of infliximab (IFX), in pediatric inflammatory bowel disease (IBD); however, few studies have compared the effect on endoscopic healing (EH) and ...
Eun Sil Kim, Sujin Choi, Sujin Choi, Byung-Ho Choe, Byung-Ho Choe, Sowon Park, Yeoun Joo Lee, Sang Jun Sohn, Soon Chul Kim, Ki Soo Kang, Kunsong Lee, Jung Ok Shim, Yu Bin Kim, Suk Jin Hong, Suk Jin Hong, Yoo Min Lee, Hyun Jin Kim, So Yoon Choi, Ju Young Kim, Yoon Lee, Ji-Sook Park, Ji-Sook Park, Jae Young Kim, Dae Yong Yi, Ji Hyuk Lee, Kwang-Hae Choi, Kwang-Hae Choi, Hyo-Jeong Jang, Hyo-Jeong Jang, In Sook Jeong, Ben Kang, Ben Kang   +31 more
doaj   +1 more source