Coagulation protease-activated receptor-2 (PAR2) promotes dyslipidemia, obesity and MASLD through repression of the hepatic pioneer factor HNF4α. [PDF]
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Position-5-driven reorientation of an immunodominant HLA-A*24:02 SARS-CoV-2 epitope drives universal T cell escape. [PDF]
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Improved patient models for simulation of clinically realistic <sup>68</sup>Ga-SSTR PET and <sup>177</sup>Lu-PRRT SPECT studies. [PDF]
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Characterization of KPC-160, a novel Ω-loop-deleted KPC variant on a dual-copy plasmid that confers cefiderocol resistance. [PDF]
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Comparative study of cardio-protective effect of metformin versus dapagliflozin in experimentally induced myocardial infarction in diabetic rats. [PDF]
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New Heterocyclic Ligands for the Adenosine Receptors P1 and for the ATP Receptors P2
ChemInform, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
BARALDI, Pier Giovanni +7 more
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P1- and P2-purine receptors in brain circulation
European Journal of Pharmacology, 1987As there is increasing evidence that purines are involved in cerebral vasodilatation, purine receptors were characterized pharmacologically in pial arteries from rabbit, cat and man, and compared with purine receptors in various non-cerebral vascular beds.
J E, Hardebo, J, Kåhrström, C, Owman
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Adenosine (P1) receptor signalling
Drug Development Research, 1996The coupling of the four defined types of adenosine receptors to G proteins and the consequent activation of effector pathways is briefly summarized. It is pointed out that the G proteins are able to influence many types of cellular effector systems, and, in particular, that the a and the β,γ-subunits may activate different signalling pathways that may
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Molecular architecture of mouse activating NKR-P1 receptors
Journal of Structural Biology, 2011Receptors belonging to NKR-P1 family and their specific Clr ligands form an alternative missing self recognition system critical in immunity against tumors and viruses, elimination of tumor cells subjected to genotoxic stress, activation of T cell dependent immune response, and hypertension.
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