Results 231 to 240 of about 398,988 (295)

Regional FDL tendon properties are regulated by biglycan in a collagen VI-independent manner. [PDF]

Matrix Biol Plus
Leiphart RJ, Weiss SN, Dyment NA, Soslowsky LJ.   +3 more
europepmc   +1 more source

The small molecule simufilam dose‐dependently attenuates the worsening of seizures in a mouse model of tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Novel epilepsy treatments for patients with tuberous sclerosis complex (TSC) and focal cortical dysplasia type II (FCDII) are urgently needed. In these patients, mutations in the mechanistic target of rapamycin (mTOR) pathway genes lead to mTOR hyperactivity and focal cortical malformations that frequently cause intractable epilepsy ...
Branden Stansley, Md. Monirul Islam, Dean J. Aguiar, Zoë Fuchs, Mackenzie Catron, Stephen Morairty, Ying Yuan, Radleigh Santos, Jingguo Hou, Annelies de Kater, George B. Thornton, Angelique Bordey   +11 more
wiley   +1 more source

Syntaxin 4 protects islet β-cells from cytokine-induced senescence. [PDF]

Front Endocrinol (Lausanne)
Ahn M, Oh E, Varghese SS, McCown EM, Bhattacharya S, Dabrowska K, Lovell BL, Hansen N, Pirrotte P, Thurmond DC, Dhawan S.   +10 more
europepmc   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Bone marrow endosteum houses Hedgehog-susceptible Dlx5-expressing osteoblast precursor cells. [PDF]

Commun Biol
Kondo K, Matsushita Y, Orikasa S, Nakai Y, Kuroda A, Ohba S, Ono W, Ono N.   +7 more
europepmc   +1 more source

DFT Insight Into Physical Properties of Halide Ions Replacements in Oxo‐Selenate Halide Compounds for Photovoltaic Application

Energy Science &Engineering, EarlyView.
Using density functional theory (CASTEP, GGA–PBE), the structural, electronic, optical, and mechanical properties of YSeO₃X (X = F, Cl, Br, and I) compounds are systematically investigated. The materials have exhibited structural stability, tunable band gaps, strong optical absorption, anisotropic ductile behavior, and promising potential for ...
Nawishta Jabeen, Ahmad Hussain, Ali Yaqoob, Omer Musa, Aseel Smerat, Joy Djuansjah   +5 more
wiley   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage. [PDF]

Adv Sci (Weinh)
Su J, Zhang S, Liang L, Bai H, Bai M, He H, Wang Y, Liu H, Liang X, Sun Y, Wu H.   +10 more
europepmc   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

p21⁺TREM2⁺ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease. [PDF]

Nat Aging
Salladay-Perez IA, Avila I, Estrada L, Alexandru AC, Ponce C, Dhingra A, Torres G, Deng CY, Hegde R, Gensheimer J, Kale A, Heckenbach I, Hui S, Edillor C, Soto JA, Napior AJ, Little I, Larsen M, Rose J, Farahi L, Lopez Gonzalez EDJ, Krieger MR, Chowdhury K, Sharma M, Jiang Y, Williams K, Scheibye-Knudsen M, Koehler CM, Meyer JG, Mack JJ, Brenner C, Bensinger SJ, Lagger C, de Magalhães JP, Schilling B, Singh R, Verdin E, Lusis AJ, Covarrubias AJ.   +38 more
europepmc   +1 more source

LncRNA Gm44981 modulates EZH2-H3K27me3-p21 axis to suppress mesangial cell senescence and kidney aging. [PDF]

Ren Fail
Li J, Wei L, Gao F, Zeng L, Jiang H, Chen L.   +5 more
europepmc   +1 more source