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p27 in Cell Cycle Control and Cancer
Leukemia & Lymphoma, 2000In order to survive, cells need tight control of cell cycle progression. The control mechanisms are often lost in human cancer cells. The cell cycle is driven forward by cyclin-dependent kinases (CDKs). The CDK inhibitors (CKIs) are important regulators of the CDKs.
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Science's STKE, 2001
In quiescent cells that have withdrawn from the cell cycle, protein translation is generally depressed by virtue of inhibition of the activity of the cap-dependent translation factor, eukaryotic initiation factor eIF4. One exception is the cyclin-dependent kinase inhibitor p27, which has high rates of expression in quiescent cells. Through
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In quiescent cells that have withdrawn from the cell cycle, protein translation is generally depressed by virtue of inhibition of the activity of the cap-dependent translation factor, eukaryotic initiation factor eIF4. One exception is the cyclin-dependent kinase inhibitor p27, which has high rates of expression in quiescent cells. Through
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Peripeti
Peripeti 27/28 © Peripeti og forfatterne Temaredaktion Erik Exe Christoffersen og Ida Krøgholt Redaktion Janicke Branth, Erik Exe Christoffersen (ansv.) Michael Eigtved, Solveig Gade, Falk Heinrich, Kjersti Hustvedt, Jens Christian Lauenstein Led, Johan Holm Mortensen, Susanne Hjelm Pedersen, Thomas Rosendal Nielsen, Laura Luise Schultz, Mads ...
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Peripeti 27/28 © Peripeti og forfatterne Temaredaktion Erik Exe Christoffersen og Ida Krøgholt Redaktion Janicke Branth, Erik Exe Christoffersen (ansv.) Michael Eigtved, Solveig Gade, Falk Heinrich, Kjersti Hustvedt, Jens Christian Lauenstein Led, Johan Holm Mortensen, Susanne Hjelm Pedersen, Thomas Rosendal Nielsen, Laura Luise Schultz, Mads ...
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