Results 51 to 60 of about 2,327,568 (312)
P2Y receptors in neurogenesis [PDF]
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012 AbstractG protein‐coupled P2Y receptors (Rs) regulate the function of embryonic and adult neural precursor cells (NPCs) which have the capacity to regenerate and give rise to cells belonging to all three major linages of the nervous system: neurons, oligodendrocytes and astrocytes.
Peter Illes +2 more
openaire +1 more source
Purinergic receptor mediated calcium signalling in urothelial cells [PDF]
, 2019 Non-neuronal ATP released from the urothelium in response to bladder stretch is a key modulator of bladder mechanosensation. Whilst non-neuronal ATP acts on the underlying bladder afferent nerves to facilitate sensation, there is also the potential for ...
Brierley, Stuart M +4 more
core +3 more sources
BMC Neuroscience, 2007 Background Adrenal chromaffin cells mediate acute responses to stress through the release of epinephrine. Chromaffin cell function is regulated by several receptors, present both in adrenergic (AD) and noradrenergic (NA) cells.
Castro Enrique +3 more
doaj +1 more source
Extracellular ATP drives systemic inflammation, tissue damage and mortality [PDF]
, 2014 Systemic inflammatory response syndromes (SIRS) may be caused by both infectious and sterile insults, such as trauma, ischemia-reperfusion or burns. They are characterized by early excessive inflammatory cytokine production and the endogenous release of ...
Brouckaert, Peter +4 more
core +1 more source
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012 AbstractBones are formed and remodeled by the coordinated actions of three key cell types. Osteoblasts, specialized connective tissue cells, deposit and then mineralize the collagenous bone matrix. Osteoclasts, which are derived from promonocytes, resorb mineralized matrix by excavating characteristic pits on bone surfaces.
Isabel R. Orriss, Timothy R. Arnett
openaire +1 more source
Acute downregulation of Cx43 alters P2Y receptor expression levels in mouse spinal cord astrocytes
Glia, 2003 Sylvia O. Suadicani +4 more
openalex +2 more sources
Journal of Neuroscience, 2007 Purinergic P2Y receptors are one of four types of Gq/11-coupled receptors in rat superior cervical ganglia (SCG) sympathetic neurons. In cultured SCG neurons, purinergic and bradykinin suppression of IM were similar in magnitude and somewhat less than ...
O. Zaika +3 more
semanticscholar +1 more source
P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes [PDF]
, 2008 ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical ...
Kirchhoff, Frank +6 more
core +1 more source
Regional differences in store-operated Ca2+ entry in the epithelium of the intact human lens [PDF]
, 2009 An elevated level of Ca2+ is an important factor in cataract, yet precisely how Ca2+ enters the lens is unknown. Lens epithelial cells contain a range of G-protein–coupled receptors and receptor tyrosine kinases that induce increases in intracellular Ca2+
Duncan, George +4 more
core +1 more source
Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow? [PDF]
, 2013 Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins.
Crawford, C. +4 more
core +2 more sources