Results 11 to 20 of about 925,787 (176)
Semaphorin 3E-Plexin D1 Axis Drives Lung Fibrosis through ErbB2-Mediated Fibroblast Activation. [PDF]
Adv Sci (Weinh)TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...
Deng Z +12 more
europepmc +2 more sources
OpMNPV p87, a baculovirus capsid protein : genetic location, nucleotide sequence, transcriptional mapping and immunochemical characterization [PDF]
A capsid protein termed p87 of the Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus (OpMNPV) was located to the HindIII-G fragment of the viral genome by Southern hybridization. A 3.6 kb segment of this region was sequenced and an 1872-nt open
Müller, Rolf
core +6 more sources
Insights into Api m 10-Isoforms and Splice Variants: More Than One Major IgE-Binding Epitope. [PDF]
Clin Transl AllergyThe structural, clinical and preclinical insights into Api m 10 and its immunodominant epitopes gained in this study provide substantial insights for the future development of active and passive VIT as well as further treatment approaches. ABSTRACT Background Honey bee venom (HBV) often triggers severe IgE‐mediated allergies.
Paulus-Tremel KE +7 more
europepmc +2 more sources
Recent progress in thermosensitive hydrogels and their applications in drug delivery area
MedComm – Biomaterials and Applications, Volume 2, Issue 3, September 2023., 2023 Review Paper highlighted the background of thermosensitive hydrogels, their properties, and their applications in transdermal, oral, ophthalmic, intravaginal, nasal, rectal, cancer therapy, and cell‐loaded drug delivery systems as shown in the preview.
Bangul Khan +10 more
wiley +1 more source
International Journal of Language &Communication Disorders, Volume 58, Issue 4, Page 1113-1132, July/August 2023., 2023 Abstract Background A number of practice barriers (e.g., time constraints, patient comorbidities and competing demands) exist as regards the evidence‐based assessment of adult language within the acute hospital setting. There is need for an evidence‐based, diagnostically validated, adaptable, comprehensive and efficient aphasia assessment. The Brisbane
Rhiannon Hounslow +2 more
wiley +1 more source
RAS‐targeted cancer therapy: Advances in drugging specific mutations
MedComm, Volume 4, Issue 3, June 2023., 2023 Personalized therapeutic strategy targeting specific mut‐RAS‐induced cancers is essential. Cancer type, RAS mutation type, activation of downstream pathways, and clinicopathological background should be comprehensively considered when designing strategies for drug combinations.
Cen Liu +7 more
wiley +1 more source
Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023 Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman +6 more
wiley +1 more source
British Journal of Pharmacology, Volume 179, Issue 24, Page 5273-5289, December 2022., 2022 Background and Purpose Donepezil, a piperidine inhibitor of acetylcholinesterase (AChE) prescribed for treatment of Alzheimer's disease, has adverse neuromuscular effects in humans, including requirement for higher concentrations of non‐depolarising neuromuscular blockers during surgery.
Robert R. Redman +4 more
wiley +1 more source
, 2023 <p>This dataset contains matrices for a numerical thermal model of a machine tool stand and input data to simulate a work process.</p><p>For more information see the description in the <a href="https://morwiki.mpi-magdeburg.mpg.de ...
Collaborative Research Centre Transregio 96 (CRC/TR 96)
core +1 more source