PI3Kγ is a novel regulator of TNFα signaling in the human colon cell line HT29/B6
We evaluated the role of class I PI3Kγ in the setting of TNFα‐mediated barrier breakdown in human HT‐29/B6 colon carcinoma cells by comparing wild‐type and PI3Kγ catalytic subunit–deficient cells. We provide evidence that loss of PI3Kγ in HT‐29/B6 cells affects basal regulation of claudin‐2, and that the scaffolding function of PI3Kγ mediates the ...
Franz‐Leonard Klaus+4 more
wiley +1 more source
Disaster communication of the Merapi slope community
This research aims to examine disaster communication performed by the community of Turgo, Purwobinangun, Pakem. Sleman. The research was conducted utilizing a qualitative method, and the data were collected through interviews and Focus Group Discussions.
Ulfah Hidayati+2 more
doaj +1 more source
Objectives To report the impact of burosumab on patient-reported outcomes (PROs) and ambulatory function in adults with X-linked hypophosphataemia (XLH) through 96 weeks.
K. Briot+29 more
semanticscholar +1 more source
Clinical profiles of subsequent stages in bipolar disorder: Results from the Dutch Bipolar Cohort
Abstract Introduction The manifestation of bipolar disorder (BD) is hypothesized to be determined by clinical characteristics such as familial loading, childhood abuse, age at onset, illness duration, comorbid psychiatric disorders, addiction, treatment resistance, and premorbid cognitive functioning.
Afra van der Markt+6 more
wiley +1 more source
Sprachenwahl und Sprachkenntnisse zukünftiger Ökonomen in Finnland: Am Beispiel der Hanken School of Economics in Vaasa [PDF]
This paper deals with language choice in terms of languages other than English and language skills of future economists at the Hanken School of Economics in Vaasa/Finland. German is the most frequently chosen language, followed by Spanish.
Margit Breckle
doaj
Social media has been identified as a factor in adolescents' adoption of risky sexual behavior. This research is here to answer whether social media has a vertical effect on adopting risky sexual behavior, given the increasing number of influencers on ...
Raidah Intizar Yusuf
doaj +1 more source
Technologies for Writing at the Private Sector Workplace [PDF]
Workplace literacy practices constitute the basis of today’s increasingly textualised work life. Due to the legislation on trade secrets, less research has been conducted on literacy practices in the private sector.
Jannika Lassus
doaj
The effectiveness of policy communication in promoting #KangPisMan program among university students
This study is aimed at measuring the effectiveness of policy communication in promoting #KangPisMan program among university students. #KangPisMan is a top priority program of Bandung Municipal Government to tackle waste management problem. In this sense,
Heni Nuraeni Zaenudin+2 more
doaj +1 more source
Combining data assimilation and machine learning to emulate a dynamical model from sparse and noisy observations: a case study with the Lorenz 96 model [PDF]
. A novel method, based on the combination of data assimilation and machine learning is introduced. The new hybrid approach is designed for a two-fold scope: (i) emulating a hidden, possibly chaotic, dynamics and (ii) predicting its future states.
J. Brajard+3 more
semanticscholar +1 more source
Acting for Change – A Communicational Perspective to Corporate Activism [PDF]
Business corporations are increasingly engaging in social and political issues through public actions and statements that have been described as corporate activism.
Saija Jantunen, Heidi Hirsto
doaj