Results 221 to 230 of about 1,820,429 (292)

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

3D Engineered Dual‐Redox Zinc‐Iodine Microbatteries for Intrinsically Safe on‐Chip Energy Storage

Advanced Science, EarlyView.
Dual‐redox Zn//I2 microbatteries enable high‐performance on‐chip energy storage by combining Zn2+ plating/stripping with reversible I−/I3− chemistry. Integrated with PANI micro‐cathode and 3D porous Au collectors, the system delivers enhanced capacity, energy, and power, advancing safe, CMOS‐compatible microsystems for next‐generation electronics ...
Nibagani Naresh, Sanat Nalini Paltasingh, Yijia Zhu, Xiaopeng Liu, Yujia Fan, Monojit Mondal, Su Jin Heo, Shuhui Li, Mingqing Wang, Shaoliang Guan, Yanzhuo Li, Georgios Nikiforidis, Shahab Akhavan, Ivan P. Parkin, Saroj Kumar Nayak, Michael De Volder, Buddha Deka Boruah   +16 more
wiley   +1 more source

European Society for Coxiellosis, Chlamydioses, Anaplasmoses and Rickettsioses – American Society for Rickettsiology joint meeting 2017

New Microbes and New Infections, 2018
P.-E. Fournier
doaj   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Microbiota and mycobiota in chronic inflammatory demyelinating polyneuropathy: clinical and pathophysiological correlations. [PDF]

Front Mol Neurosci
Andrusiów S, Brzoza A, Łacina P, Dratwa-Kuzmin M, Raczkowska J, Kujawa D, Romańczuk K, Gancarek M, Bochen P, Dziadkowiak E, Szponar B, Łaczmański Ł, Koszewicz M, Bogunia-Kubik K.   +13 more
europepmc   +1 more source

Spatially Separated Redox Centers in One‐Dimensional Sp2‐Carbon Covalent Organic Frameworks Enable Synergistic Photocatalytic Palladium Recovery and Bisphenol A Mineralization

Advanced Science, EarlyView.
A one‐dimensional sp2‐carbon covalent organic framework with spatially segregated redox centers integrates a dual photosensitizing system and a cationic interface for synergistic photocatalysis. The material achieves exceptional palladium recovery (1749 mg g−1) and bisphenol A mineralization (0.1710 min−1) without sacrificial agents, demonstrating ...
Yi‐Ru Chen, Jing‐Yi Li, Yao Xiao, Dan Zhong, Lu Zhang, Yu‐Ting Xie, Xiu Wang, Yibao Li, Wei‐Rong Cui, Jian‐Ding Qiu   +9 more
wiley   +1 more source

High-throughput small-angle X-ray scattering reveals effective structure factor transitions linked to high-concentration antibody viscosity. [PDF]

MAbs
Kalejaye L, Wu IE, Chu JM, Shah M, Castellanos MM, Chodankar S, Mody N, Lai PK.   +7 more
europepmc   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source