Results 61 to 70 of about 28,233,756 (286)
Here, a nonlocal nonlinear operator known as the fractional ( p , q ) $(p,q)$ -Laplacian is considered. The existence of a mountain pass solution is proved via critical point theory and variational methods.
F. Behboudi, A. Razani, M. Oveisiha
doaj +1 more source
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
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CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
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Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
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Bi-Periodic (p,q)-Fibonacci and Bi-Periodic (p,q)-Lucas Sequences
In this paper, we define bi-periodic (p,q)-Fibonacci and bi-periodic (p,q)-Lucas sequences, which generalize Fibonacci type, Lucas type, bi-periodic Fibonacci type and bi-periodic Lucas type sequences, using recurrence relations of (p,q)-Fibonacci and (p,
Yasemin Taşyurdu +1 more
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
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(g, K)-module of O(p, q) associated with the finite-dimensional representation of sl(2) [PDF]
The main aim of this paper is to show that one can construct (????,K)-modules of O(p,q) associated with the finite-dimensional representation of ????????2 by quantizing the moment map on the symplectic vector space (ℂp+q) ℝ and using the fact that (O(p,q)
橋本, 隆司 +5 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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