Results 101 to 110 of about 218,902 (300)

Electrochemical Hofmann Rearrangement for Modular Synthesis of Unsymmetrical Ureas and Late‐Stage Modification of Drugs

Advanced Science, EarlyView.
An electrochemical Hofmann rearrangement of amide involving amine or other amide nucleophiles has been developed. The use of NaI guarantees the feasibility and compatibility of the electrosynthesis protocol, which enables highly chemoselective synthesis of unsymmetrical N‐acylureas from two different amides, as well as the production of unsymmetrical ...
Xue‐Qing Mou, Xiao Zha, Yu‐Rui Jian, Shao‐Xing Zhong, Xin‐Yu Fu, Sheng‐Yang Xu, Wei Xiang, Bao‐Dong Cui, Yun Zhang, Yong‐Zheng Chen   +9 more
wiley   +1 more source

Free Polyethylenimine Enhances Substrate-Mediated Gene Delivery on Titanium Substrates Modified With RGD-Functionalized Poly(acrylic acid) Brushes

Frontiers in Chemistry, 2019
Substrate mediated gene delivery (SMD) is a method of immobilizing DNA complexes to a substrate via covalent attachment or nonspecific adsorption, which allows for increased transgene expression with less DNA compared to traditional bolus delivery.
Amy Mantz, Amy Mantz, Alice Rosenthal, Alice Rosenthal, Eric Farris, Tyler Kozisek, Eva Bittrich, Saghar Nazari, Eva Schubert, Eva Schubert, Mathias Schubert, Mathias Schubert, Mathias Schubert, Mathias Schubert, Mathias Schubert, Manfred Stamm, Manfred Stamm, Petra Uhlmann, Petra Uhlmann, Angela K. Pannier, Angela K. Pannier   +20 more
doaj   +1 more source

Synthesis and Aggregation Behavior of Pluronic F87/Poly(acrylic acid) Block Copolymer with Doxorubicin [PDF]

, 2005
Poly(acrylic acid) (PAA) was grafted onto both termini of Pluronic F87 (PEO₆₇-PPO₃₉-PEO₆₇) via atom transfer radical polymerization to produce a novel muco-adhesive block copolymer PAA₈₀-b-F₈₇-b-PAA₈₀.
Bromberg, Lev, Hatton, T. Alan, Ravi, P., Tam, K. C., Tian, Y.   +4 more
core  

Scalable, Low‐Cost, Freeze‐Resistant Hydrogels by Alkali‐Polyphenol‐Triggered Polymerization for Low‐Temperature Self‐Powered Triboelectric Sensor

Advanced Science, EarlyView.
Leveraging the multidimensional self‐catalytic merits of the alkali‐polyphenol synergistic self‐catalytic platform, this work delineates the intrinsic mechanism governing the regulation of hydrogel properties and puts forward an innovative design paradigm for frost‐tolerant electrode materials, providing critical scientific insights and technical ...
Mengting Zhou, Yaru Bao, Chunpeng Li, Caicai Li, Gaobo Lou, Shaochao Sun, Zhezhe Zhou, Gaojie Jiao, Xiaochun Zhang, Pingan Song, Dan Sun   +10 more
wiley   +1 more source

Structurally Enhanced Colloidal Molecules via Carbene‐Mediated Covalent C─H Insertion Crosslinking

Advanced Science, EarlyView.
This work presents a nonspecific covalent crosslinking strategy to significantly enhance the structural stability of colloidal molecules (CMs) without compromising their inherent structural and physicochemical properties by rationally designing a diazo‐based crosslinker.
Liwei Dai, Chongyang Yao, Xiancheng Zhang, Weijia Kong, Mingxing Liu, Huibin He, Yutao Sang, Zhihong Nie   +7 more
wiley   +1 more source

Autonomous and Continuous Atmospheric Water Harvesting Using Modified Wood

Advanced Science, EarlyView.
A rigid, hydroxyl‐rich wood skeleton with graded channels is used as a multifunctional host to co‐incorporate a PNipam/PAA network and LiCl, creating a high‐performance sorbent for atmospheric water harvesting. The composite achieves rapid sorption, efficient low‐temperature desorption, and stable cycling, enabling a solar‐powered device with a high ...
Shiheng He, Jiaqi Su, Tianting Leng, Yujian Song, Jidong Dong, Pengfei Huo, Zhenhua Gao, Shuaiyuan Han   +7 more
wiley   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Synergistic Dual Slip‐Link Toughening of a Water‐Rich Double Network Hydrogel Combining Slide‐Ring and Highly Entangled Networks

Advanced Science, EarlyView.
Two distinct slip‐link mechanisms – the slide‐ring pulley effect and highly entangled chains – are combined in a water‐rich double network hydrogel, achieving synergistic toughening, near‐complete reversibility, and exceptional friction tear resistance at >$>$91 wt.% water.
Subhankar Mandal, Saleh Assadi, Aseem Milind Visal, Ignacio Lorente Montero, Franck J. Vernerey, Carson J. Bruns   +5 more
wiley   +1 more source

Enhancing the food security of the peri-urban and urban poor through improvements to the quality, safety and economics of street-vended foods [PDF]

There has been a continuing growth in urbanisation in developing countries, and governments’ face a major challenge in ensuring that city dwellers are able to procure sufficient food. Street foods are sold in almost every country in the world.
Johnson, Paa-Nii T., Yawson, Robert M.
core   +1 more source

Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum. [PDF]

, 2019
BackgroundAcute kidney injury (AKI) is one of the major risk factors for progression to chronic kidney disease (CKD) and renal fibrosis. However, effective therapies remain poorly understood.
Cao, Gang, Chen, Dan-Qian, Chen, Lin, Guo, Yan, Vaziri, Nosratola D, Wang, Ming, Yang, Tian, Zhao, Hui, Zhao, Ying-Yong   +8 more
core   +1 more source