Results 81 to 90 of about 4,096 (155)
Skin microbiome engineering: Challenges and opportunities in skin diseases treatment
iMetaOmics, Volume 2, Issue 2, June 2025.The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley +1 more source
mGluR5 in Pyramidal Neurons in the Hippocampus Mediates Chronic Stress‐Induced Memory Deficits
CNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.Diagrammatic representation of the role of mGluR5 in controlling memory impairments brought on by chronic stress. Chronic stress caused memory impairment, decreased GABAergic synaptic inputs, and decreased mGluR5 and PACAP levels in the hippocampus CA1.
Hong‐Cheng Lu +5 more
wiley +1 more source
PAC1 receptor (ADCYAP1R1) genotype and problematic alcohol use in a sample of young women
Neuropsychiatric Disease and Treatment, 2017 Wojciech Łukasz Dragan,1 Piotr M Czerski,2 Małgorzata Dragan3 1The Interdisciplinary Center for Behavior Genetic Research, Faculty of Psychology, University of Warsaw, Warsaw, 2Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences ...
Dragan WŁ, Czerski PM, Dragan M
doaj
Platelets, 2019 Platelet quality in different platelet concentrates (PCs) has been the subject of several studies. Nonetheless, there is a lack of robust data on the correlation and agreement among platelet function tests as a prerequisite for the association of PC ...
Lars Asmis +3 more
doaj +1 more source
Discovery of PACAP and its receptors in the brain
The Journal of Headache and Pain, 2018 Pituitary adenylate-cyclase-activating polypeptide (PACAP) is a 27- or 38-amino acid neuropeptide, which belongs to the vasoactive intestinal polypeptide (VIP)/glucagon/secretin family. PACAP shows particularly high homology (~ 68%) to VIP.
Takahiro Hirabayashi +2 more
doaj +1 more source
Probing PAC1 receptor activation across species with an engineered sensor
eLifeClass-B1 G-protein-coupled receptors (GPCRs) are an important family of clinically relevant drug targets that remain difficult to investigate via high-throughput screening and in animal models. Here, we engineered PAClight1 P78A , a novel genetically encoded sensor based on a class-B1 GPCR ...
Cola, Reto B +13 more
openaire +4 more sources
Caracterización biológica de tres aislamientos naturales del Rubulavirus porcino (México)
Revista de Biología Tropical, 2008 El Rubulavirus porcino causa un síndrome neurológico y reproductivo en cerdos, hasta ahora reportado sólo en México. Los virus aislados se agrupan de acuerdo con los síntomas principales observados durante los brotes en: a) neutrópicos en lechones, b ...
María del Tránsito Borraz-Argüello +4 more
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Urotensin II-induced signaling involved in proliferation of vascular smooth muscle cells
Vascular Health and Risk Management, 2010 Myriam Iglewski, Stephen R GrantDepartment of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, Texas, USAAbstract: The urotensin II receptor, bound by the ligand urotensin II, generates second ­messengers, ie ...
Myriam Iglewski, Stephen R Grant
doaj
An RBPMS-driven splicing regulatory axis including MBNL1, RBFOX2, and QK promotes smooth muscle cell contractile identity. [PDF]
Nucleic Acids ResHuang Y +7 more
europepmc +1 more source