Results 101 to 110 of about 2,251,963 (386)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Conceptul de agresiune în doctrina dreptului internaţional public contempran
Revista Institutului Naţional de Justiţie, 2019 Este incontestabil rolul codificării oficiale a unei norme internaţionale prin intermediul unor acorduri internaţionale. Cu toate acestea, o importanţă deosebită îi revine codificării neoficiale, realizată, în special, în baza lucrărilor oamenilor de ...
Roşca Valentin
doaj
Curationis, 1983 Artificial cardiac pacing, the use of electrical stimuli to cause contraction of heart muscle, is a sophisticated therapeutic and diagnostic tool. Its rapid technologic improvement since first developed in the late 1930’s by Hyman, has made it possible not only to avoid certain cases of death due to heart block, but also to extend and improve the ...
openaire +3 more sources
Digital world, lifeworld, and the phenomenology of corporeality [PDF]
, 2019 The contemporary world is characterised by the pervasive presence of digital technologies that play a part in almost every aspect of our life. An urgent and much-debated issue consists in evaluating the repercussions of these technologies on our human ...
Pace Giannotta, Andrea
core
The Cusp/Core problem: supernovae feedback versus the baryonic clumps and dynamical friction model
, 2016 In the present paper, we compare the predictions of two well known mechanisms considered able to solve the cusp/core problem (a. supernova feedback; b. baryonic clumps-DM interaction) by comparing their theoretical predictions to recent observations of ...
Del Popolo, A., Pace, F.
core +1 more source
Evolution of sex-specific pace-of-life syndromes: genetic architecture and physiological mechanisms
Behavioral Ecology and Sociobiology, 2018 Sex differences in life history, physiology, and behavior are nearly ubiquitous across taxa, owing to sex-specific selection that arises from different reproductive strategies of the sexes.
Elina Immonen +3 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
MedicinaBackground and Objectives: Recent advances in dentistry include microbiological and metabolomic analyses, which have the potential to improve the understanding of oral microbiome–host imbalances during orthodontic treatment.
Michela Boccuzzi +5 more
doaj +1 more source
Suppression of Star Formation in the Hosts of Low-Excitation Radio Galaxies
, 2015 The feedback from radio-loud active galactic nuclei (R-AGN) may help maintain low star formation (SF) rates in their early-type hosts, but the observational evidence for this mechanism has been inconclusive.
Pace, Cameron, Salim, Samir
core +1 more source