Results 161 to 170 of about 2,050,605 (416)

The Accelerating Pace of Star Formation

open access: yes, 2017
We study the temporal and spatial distribution of star formation rates in four well-studied star-forming regions in local molecular clouds(MCs): Taurus, Perseus, $\rho$ Ophiuchi, and Orion A.
Caldwell, Spencer, Chang, Philip
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

A Practical Guide to Budget Pacing Algorithms in Digital Advertising [PDF]

open access: yesarXiv
A typical real-time ad-serving funnel comprises ad targeting, conversion modeling (e.g., click-through rate prediction), budget pacing (bidding), and auction processes. While there is a wealth of research and articles on ad targeting and conversion modeling, budget pacing,a crucial component,lacks a systematic treatment specifically tailored for ...
arxiv  

Impact of early personal‐history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan

open access: yesAging Cell, 2017
Therapies to extend healthspan are poised to move from laboratory animal models to human clinical trials. Translation from mouse to human will entail challenges, among them the multifactorial heterogeneity of human aging.
Daniel W Belsky   +6 more
semanticscholar   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Utilizing C. elegans Spermatogenesis and Fertilization Mutants as a Model for Human Disease

open access: yesJournal of Developmental Biology
The nematode C. elegans is a proven model for identifying genes involved in human disease, and the study of C. elegans reproduction, specifically spermatogenesis and fertilization, has led to significant contributions to our understanding of cellular ...
Sofia M. Perez   +2 more
doaj   +1 more source

Microfinance and the Decision to Invest in Children’s Education

open access: yesInternational Journal of Financial Studies, 2018
Although one of the primary objectives of microfinance has been the reduction of poverty through the provision of credit for income-generating purposes, evidence of its impact on poverty has been mixed.
PV Viswanath
doaj   +1 more source

Slow pace of antileishmanial drug development

open access: yes, 2018
The protozoan parasite Leishmania is endemic in large parts of the world which causes leishmaniasis. Its visceral form is fatal if not treated and is caused mostly by Leishmania donovani, Leishmania infantum and Leishmania chagasi. Given the difficulties
Awanish Kumar, S. Pandey, M. Samant
semanticscholar   +1 more source

Temporary pacing

open access: yesCurationis, 1983
Artificial cardiac pacing, the use of electrical stimuli to cause contraction of heart muscle, is a sophisticated therapeutic and diagnostic tool. Its rapid technologic improvement since first developed in the late 1930’s by Hyman, has made it possible not only to avoid certain cases of death due to heart block, but also to extend and improve the ...
openaire   +3 more sources

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