Results 181 to 190 of about 2,050,605 (416)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Protocol: What works to increase the use of evidence for policy decision‐making: A systematic review

open access: yesCampbell Systematic Reviews
This is the protocol for a Campbell systematic review. The objectives are as follows: Our aim is to collect, assess, and synthesise all the available empirical evidence on what works to support evidence‐informed decision‐making by policymakers.
Promise Nduku   +7 more
doaj   +1 more source

Looking for melanoma [PDF]

open access: yes, 2010
Melanoma is increasing worldwide and UK death rates from melanoma have more than doubled from 1.2 per 100,000 in 1971 to 2.6 per 100,000 in 2007. Cancer Research UK predicts that by 2024, rates of malignant melanoma in people aged 60 to 79 will ...
Pace, Joseph L.
core  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

The Primal Scream: Re-Reading the “Temporality” Chapter of Phenomenology of Perception in the Context of Negative Philosophy

open access: yesPhilosophies
Merleau-Ponty’s specific theory of negation has received surprisingly little attention within the literature. Given his engagement with Sartre, not to mention Hegel and Marx, one would think that this concept and its surrounding issues and problems would
Keith Whitmoyer
doaj   +1 more source

Color Relationism and Enactive Ontology [PDF]

open access: yes, 2018
In this paper, I present the enactive theory of color that implies a form of color relationism. I argue that this view constitutes a better alternative to color subjectivism and color objectivism.
Pace Giannotta, Andrea
core  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

The Concept of Experience in Husserl's Phenomenology and James' Radical Empiricism [PDF]

open access: yes, 2018
In this paper, I develop a comparison between the philosophies of Husserl and James in relation to their concepts of experience. Whereas various authors have acknowledged the affinity between James’ early psychology and Husserl’s phenomenology, the late ...
Pace Giannotta, Andrea
core  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

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